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多层面干预以消除丹麦南部地区的丙型肝炎:C-Free-South 项目。

A multi-level intervention to eliminate hepatitis C from the Region of Southern Denmark: the C-Free-South project.

机构信息

Department of Infectious Diseases, Odense University Hospital, J. B. Winsloews Vej 4, Indgang 18 Penthouse 2. sal, 5000, Odense C, Denmark.

Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, Winsløwparken 19, 3. sal, 5000, Odense, Denmark.

出版信息

BMC Infect Dis. 2022 Mar 1;22(1):202. doi: 10.1186/s12879-022-07196-7.

DOI:10.1186/s12879-022-07196-7
PMID:35232372
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8889755/
Abstract

Denmark has signed the WHO strategy to eliminate hepatitis C virus (HCV). In the absence of a national strategy for elimination, a local action plan was developed in the Region of Southern Denmark (RSD). The aim of the strategy is to diagnose 90% of HCV-infected persons and treat 80% of those diagnosed by 2025. The strategy was developed by reviewing Danish data on HCV epidemiology and drug use to identify key populations for screening, linkage to care, and treatment. Based on available published data from 2016, an estimated 3028 persons in the RSD were HCV-RNA positive (population prevalence 0.21%). Of these, 1002 were attending clinical care, 1299 were diagnosed but not in clinical care, and 727 were undiagnosed. Three different interventions targeting the HCV-infected population and two interventions for HCV surveillance are planned to achieve elimination. The "C-Free-South" strategy aims to eliminate HCV in our region by identifying (90%) and treating (80%) of infected persons by the end of 2025, 5 years earlier than the WHO elimination target date.

摘要

丹麦签署了世界卫生组织(WHO)消除丙型肝炎病毒(HCV)战略。在缺乏国家消除战略的情况下,南丹麦地区(RSD)制定了一项地方行动计划。该战略的目标是到 2025 年,诊断出 90%的 HCV 感染者,并治疗其中 80%的感染者。该战略是通过审查丹麦 HCV 流行病学和药物使用数据制定的,旨在确定关键人群进行筛查、护理联系和治疗。根据 2016 年可用的已发表数据,估计 RSD 中有 3028 人 HCV-RNA 阳性(人群流行率为 0.21%)。其中,1002 人正在接受临床治疗,1299 人已诊断但未接受临床治疗,727 人未被诊断。计划实施三种针对 HCV 感染者人群的干预措施和两种 HCV 监测干预措施,以实现消除目标。“C-Free-South”战略旨在通过到 2025 年底识别(90%)和治疗(80%)感染者,在世界卫生组织消除目标日期之前提前 5 年消除我们地区的 HCV。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/874f/8889755/833e431dc0c3/12879_2022_7196_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/874f/8889755/833e431dc0c3/12879_2022_7196_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/874f/8889755/833e431dc0c3/12879_2022_7196_Fig1_HTML.jpg

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