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[脂质过氧化在病毒性肝炎发病机制中的作用]

[The role of lipid peroxidation in the pathogenesis of viral hepatitis].

作者信息

Abakumov G Z, Novitskiĭ G K, Legon'kova L F

出版信息

Vopr Med Khim. 1988 Nov-Dec;34(6):30-2.

PMID:3238939
Abstract

Content of blood bilirubin was increased 3.3-11.4-fold as well as 4-10-activation of alanine aminotransferase and glutathione S-transferase was found in patients with virus hepatitis as compared with normal state. At the same time, lipid peroxidation was activated 1.9-3.5-fold in blood plasma as shown by means of chemoluminescence procedure, while the antioxidative activity was decreased 2.2-2.3-fold.

摘要

与正常状态相比,病毒性肝炎患者血液胆红素含量增加了3.3至11.4倍,同时还发现丙氨酸转氨酶和谷胱甘肽S转移酶被激活了4至10倍。与此同时,通过化学发光法检测发现,血浆中脂质过氧化反应被激活了1.9至3.5倍,而抗氧化活性降低了2.2至2.3倍。

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