Division of Abdominal Transplantation, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX; Texas Children's Hospital, Houston, TX.
Division of Abdominal Transplantation, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX; Texas Children's Hospital, Houston, TX.
Transplant Proc. 2020 Nov;52(9):2824-2826. doi: 10.1016/j.transproceed.2020.02.154. Epub 2020 May 7.
Reports on the long-term outcomes and immunosuppressive regimens of multiorgan transplant patients are limited. Here, we describe a patient with cystic fibrosis complicated by multiorgan failure who was successfully treated with combined liver lung transplant and delayed kidney transplant, resulting in excellent outcomes. Delayed kidney transplant was done to reduce the operative stress of a single procedure, giving time for adequate resuscitation and weaning from vasopressors. Our patient's postoperative course was complicated by post-transplant lymphoproliferative disease, which was successfully treated with rituximab and reduced dosages of immunosuppression.
有关多器官移植患者的长期预后和免疫抑制方案的报告有限。在这里，我们描述了一位患有囊性纤维化合并多器官衰竭的患者，他成功地接受了肝肺联合移植和延迟肾移植治疗，取得了极好的结果。延迟肾移植是为了减少单次手术的操作压力，为充分复苏和逐渐减少血管加压药的使用争取时间。我们患者的术后病程复杂，发生了移植后淋巴组织增生性疾病，通过利妥昔单抗和减少免疫抑制剂剂量成功治疗。
