Hamabira Koichi, Kita Yoshiaki, Mori Shinichiro, Tanabe Kan, Omoto Itaru, Arigami Takaaki, Iino Satoshi, Maemura Kosei, Natsugoe Shoji
Dept. of Digestive Surgery, Breast and Thyroid Surgery, Kagoshima University Graduate School of Medical and Dental Sciences.
Gan To Kagaku Ryoho. 2020 Apr;47(4):640-642.
A woman in her 50s received a detailed examination for her abdominal pain. CT indicated intestinal wall thickening of the ascending colon, lymphadenopathy, and tumor embolism in the superior mesenteric vein. Colonoscopy revealed type 2 tumor in the hepatic flexure of the colon, and she was diagnosed as having moderately differentiated adenocarcinoma by biopsy specimen. She received 12 courses of FOLFOXIRI plus BV therapy after ileostomy. As the tumor embolism disappeared and the primary lesion shrank after chemotherapy, right hemicolectomy and lymph node dissection were performed. Six months after surgery, she has had no recurrent disease. This case suggests that FOLFOXIRI plus BV therapy could be an effective treatment for right colon cancer with tumor embolism.
一名50多岁的女性因腹痛接受了详细检查。CT显示升结肠肠壁增厚、淋巴结肿大以及肠系膜上静脉肿瘤栓塞。结肠镜检查发现结肠肝曲有2型肿瘤,活检标本诊断为中度分化腺癌。她在回肠造口术后接受了12个疗程的FOLFOXIRI加贝伐单抗治疗。化疗后肿瘤栓塞消失且原发灶缩小,遂行右半结肠切除术及淋巴结清扫术。术后6个月,她未出现疾病复发。该病例提示FOLFOXIRI加贝伐单抗治疗可能是伴有肿瘤栓塞的右结肠癌的有效治疗方法。