Segi Yuki, Yamamoto Masato, Tsuji Naoya, Nakamura Shinichiro, Nakamura Shunta, Kobayashi Motoyuki, Taniguchi Kentaro, Kato Kenji, Iwata Makoto, Tabata Masami
Dept. of Surgery, Matsusaka Chuo General Hospital.
Gan To Kagaku Ryoho. 2022 Dec;49(13):1479-1481.
The progression of intravenous tumor thrombus in colorectal cancer is rare and reports on its resection are limited. This study reports a case of ascending colon cancer with a tumor thrombus in the superior mesenteric vein(SMV). A 44-year-old woman was admitted to our hospital for right, lower abdominal pain. Dynamic CT revealed an enhanced mass in the ascending colon and a tumor thrombus in the SMV. She was diagnosed with ascending colon cancer and an SMV tumor thrombus. An extended right hemicolectomy was performed. The SMV tumor thrombus extended from the gastrocolic trunk (GCT)to the right gastroepiploic vein and the anterior superior pancreaticoduodenal vein. To remove the tumor thrombus, a wedge-shaped incision was made through the SMV. Pathological examination showed a moderately differentiated adenocarcinoma of the ascending colon with extra-regional lymph node metastasis(No. 6)and intrapancreatic venous invasion. The pathological staging was pT4b, pN0, pM1a, pStage Ⅳa(Japanese Classification 9th edition). The patient was discharged on day 13 postoperatively. After discharge, 14 courses of mFOLFOX6 plus bevacizumab chemotherapy were administered. The patient is currently alive with no recurrence 15 months postoperatively.
结直肠癌中静脉内肿瘤血栓的进展较为罕见,关于其切除术的报道有限。本研究报告了一例升结肠癌伴肠系膜上静脉(SMV)肿瘤血栓的病例。一名44岁女性因右下腹痛入住我院。动态CT显示升结肠有强化肿块及SMV内肿瘤血栓。她被诊断为升结肠癌伴SMV肿瘤血栓。行扩大右半结肠切除术。SMV肿瘤血栓从胃结肠干(GCT)延伸至右胃网膜静脉和胰十二指肠上前静脉。为切除肿瘤血栓,在SMV上做了楔形切口。病理检查显示升结肠中分化腺癌伴区域外淋巴结转移(第6组)及胰腺内静脉侵犯。病理分期为pT4b、pN0、pM1a、p Ⅳa期(日本第9版分类)。患者术后第13天出院。出院后给予14个疗程的mFOLFOX6加贝伐单抗化疗。患者术后15个月仍存活,无复发。