Terashima Takahiro, Kawamoto Shunji, Maekawa Kouichi, Shinozaki Nobuaki, Kuroki Norimitsu
Dept. of Surgery, Shonan Atsugi Hospital.
Gan To Kagaku Ryoho. 2020 Apr;47(4):688-690.
A 68-year-old man with jaundice was diagnosed with pancreatic cancer. The tumor seemed to invade the portal vein, the common hepatic artery, and the splenic artery plexus. The initial diagnosis was unresectable pancreatic cancer. The patient was treated with gemcitabine plus nab-paclitaxel therapy. The tumor reduced in size, and invasion of the main vessels was alleviated after 3 courses. Therefore, we performed total pancreatectomywith total gastrectomy. Histopathological findings showed pancreatic adenocarcinoma, T4(PV)N2M0, fStage Ⅳb, R0. There are reports of curative resection for unresectable pancreatic cancer after chemotherapy. However, the majorityof these reports were about pancreatoduodenectomyor distal pancreatectomy. We present a rare case of curative total pancreatectomy after chemotherapy.
一名68岁的黄疸男性被诊断为胰腺癌。肿瘤似乎侵犯了门静脉、肝总动脉和脾动脉丛。初步诊断为不可切除的胰腺癌。该患者接受了吉西他滨加纳米白蛋白结合型紫杉醇治疗。3个疗程后肿瘤体积缩小，主要血管侵犯减轻。因此，我们进行了全胰切除术加全胃切除术。组织病理学结果显示为胰腺腺癌，T4（PV）N2M0，f分期Ⅳb期，R0。有关于化疗后不可切除胰腺癌行根治性切除术的报道。然而，这些报道大多是关于胰十二指肠切除术或胰体尾切除术。我们报告了一例化疗后行根治性全胰切除术的罕见病例。
