Department of Psychiatry, Psychotherapy and Psychosomatics, Medical School, RWTH Aachen University, Aachen, Germany.
Deutsche Gesellschaft für Osteopathische Medizin (DGOM), Mannheim, Germany.
Psychophysiology. 2020 Sep;57(9):e13594. doi: 10.1111/psyp.13594. Epub 2020 May 10.
Supratentorial brain structures such as the insula and the cingulate cortex modulate the autonomic nervous system (ANS). The neural underpinnings of separate frequency bands for variability in cardiac and respiratory data have been suggested in explaining parasympathetic and sympathetic ANS modulation. As an extension, an intermediate (IM) band in peripheral physiology has been considered to reflect psychophysiological states during rest. Using functional magnetic resonance imaging (fMRI), we investigated the neural correlates associated with IM band variability in cardiac and respiratory rate and identified dissociable networks for LF, IM, and HF bands in both modalities. Cardiac and respiratory IM band fluctuations correlated with blood oxygen level-dependent (BOLD) signal in the mid and posterior insula and the secondary somatosensory area, that is, regions related to interoceptive perception. These data suggest that in addition to the commonly considered LF and HF bands, other frequency components represent relevant physiological constituents. The IM band may be instrumental for assessment of the CNS-ANS interaction. In particular, the relation between the IM band and interoception may be of physiological and clinical interest.
脑岛和扣带回等幕上脑结构调节自主神经系统 (ANS)。有人提出，心脏和呼吸数据变异性的不同频带的神经基础可以解释副交感和交感 ANS 调节。作为扩展，外周生理学中的中间 (IM) 带被认为可以反映休息时的心理生理状态。使用功能磁共振成像 (fMRI)，我们研究了与心率和呼吸率的 IM 带变异性相关的神经相关性，并在两种模式下确定了 LF、IM 和 HF 带的可分离网络。心脏和呼吸 IM 带的波动与中脑和后岛以及次级体感区的血氧水平依赖 (BOLD) 信号相关，即与内脏感知相关的区域。这些数据表明，除了通常考虑的 LF 和 HF 频带外，其他频率成分也代表相关的生理成分。IM 频带可能对评估中枢神经系统-ANS 相互作用很重要。特别是，IM 频带与内脏感知之间的关系可能具有生理和临床意义。
