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同种异体骨移植用于髋关节翻修术中股骨缺损的扩大:病例系列

Allogenic bone graft for femoral defect augmentation in hip revision arthroplasty: A case series.

作者信息

Wirries Nils, Skutek Michael, Örgel Marcus, Budde Stefan, Derksen Alexander, Windhagen Henning, Flörkemeier Thilo

机构信息

Diakovere Annastift Hannover.

Hannover Medical School, Hannover, Germany.

出版信息

Orthop Rev (Pavia). 2020 Apr 28;12(1):8173. doi: 10.4081/or.2020.8173. eCollection 2020 Apr 22.

DOI:10.4081/or.2020.8173
PMID:32391131
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7206367/
Abstract

Cortical bone loss in revision hip arthroplasty requires an adequate stabilization to achieve a durable implant fixation. This case series shall illustrate possible indications for the use of allogenic grafts in revision hip arthroplasty. Twelve patients with femoral bone loss were treated with allografts. In addition to established clinical scores, the radiological follow-ups were analyzed for hints of implants loosening and the osteointegration of the allografts. After a mean follow-up of 3.0 years the mHHS was 61.3 points and the UCLA 3.8. One patient showed a non-progressive radiolucency around the hip implant. The osteointegration of all allogenic grafts happened on time. Up to the last follow-up no revision surgery of the hip implants and the associated femoral bone graft was observed. Allogenic bone grafts present a method for biological stabilization in situations of large femoral cortical bone defects in revision hip arthroplasty.

摘要

髋关节翻修术中的皮质骨丢失需要充分稳定以实现持久的植入物固定。本病例系列将说明同种异体移植物在髋关节翻修术中的可能适应证。12例股骨骨丢失患者接受了同种异体移植物治疗。除了既定的临床评分外,还对影像学随访进行了分析,以寻找植入物松动和同种异体移植物骨整合的迹象。平均随访3.0年后,改良Harris髋关节评分(mHHS)为61.3分,加州大学洛杉矶分校(UCLA)评分3.8分。1例患者在髋关节植入物周围出现非进行性透光影。所有同种异体移植物均按时发生骨整合。直至最后一次随访,未观察到髋关节植入物及相关股骨骨移植的翻修手术。同种异体骨移植为髋关节翻修术中股骨皮质骨大缺损情况下的生物稳定提供了一种方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0862/7206367/9e37dfab904c/or-12-1-8173-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0862/7206367/9e37dfab904c/or-12-1-8173-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0862/7206367/9e37dfab904c/or-12-1-8173-g001.jpg

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本文引用的文献

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Proximal Femoral Allograft-Prosthetic Composites: Do They Really Restore Bone? A Retrospective Review of Revision Allograft-Prosthetic Composites.股骨近端同种异体移植物-假体复合材料:它们真的能重建骨吗?翻修同种异体移植物-假体复合材料的回顾性研究。
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Cortical Strut Allograft Support of Modular Femoral Junctions During Revision Total Hip Arthroplasty.翻修全髋关节置换术中模块化股骨连接处的皮质支撑异体骨移植
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Short- to long-term follow-up of total femoral replacement in non-oncologic patients.
非肿瘤患者全股骨置换的短期至长期随访
BMC Musculoskelet Disord. 2016 Dec 12;17(1):498. doi: 10.1186/s12891-016-1355-6.
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Management of femoral bone loss in revision total hip arthroplasty.翻修全髋关节置换术中股骨骨缺损的处理
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High Survivorship With Cementless Stems and Cortical Strut Allografts for Large Femoral Bone Defects in Revision THA.非骨水泥型股骨柄与皮质支撑异体骨移植用于翻修全髋关节置换术中大股骨骨缺损的高生存率
Clin Orthop Relat Res. 2015 Sep;473(9):2990-3000. doi: 10.1007/s11999-015-4358-y. Epub 2015 May 27.
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Management bone loss of the proximal femur in revision hip arthroplasty: Update on reconstructive options.髋关节翻修术中股骨近端骨丢失的处理:重建选择的最新进展
World J Orthop. 2014 Nov 18;5(5):614-22. doi: 10.5312/wjo.v5.i5.614.
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Management of Vancouver type B2 and B3 femoral periprosthetic fractures using an uncemented extensively porous-coated long femoral stem prosthesis.使用非骨水泥型大孔隙涂层长柄股骨假体治疗温哥华B2型和B3型股骨假体周围骨折
Eur J Orthop Surg Traumatol. 2013 Jul;23(5):545-52. doi: 10.1007/s00590-012-1024-x. Epub 2012 Jun 14.
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Orthop Traumatol Surg Res. 2013 Feb;99(1):30-6. doi: 10.1016/j.otsr.2012.09.016. Epub 2012 Dec 19.
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