Kahl N, Böhm E, Arcq M
Chirurgische Klinik, Ruhr-Universität Bochum.
Z Orthop Ihre Grenzgeb. 1988 Sep-Oct;126(5):487-91. doi: 10.1055/s-2008-1044472.
For the research here presented, a total of 15 femoral heads with idiopathic necrosis in 15 patients, ranging in the age from 28 to 59 years, were available. In 7 of the histologically examined, in the occasion of endoprosthetic obtained femoral heads, a singular necrosis was to be discovered. In 6 items two attacks of necrosis, in 2 even three attacks could be confined. The comparison of these results with the clinically obtained case history showed that the second as well as the third attack of necrosis occurred during the first two years of the disease and partly obvious due to the increase of subjective symptoms. With the knowledge of these facts, it may be assumed that by means of exact observation of the patients concerned, even after diagnosis has been made, valuable tips to solve the up to now still unknown etiology of idiopathic avascular necrosis could be won.
在本研究中,共有15例患有特发性坏死的患者提供了15个股骨头,患者年龄在28岁至59岁之间。在7例经组织学检查的因植入假体而获得的股骨头中,发现有单发坏死。在6例中发现有两次坏死发作,在2例中甚至发现有三次坏死发作。将这些结果与临床获得的病例史进行比较表明,第二次以及第三次坏死发作发生在疾病的头两年,部分是由于主观症状的加重而明显。鉴于这些事实,可以假设,通过对相关患者进行精确观察,即使在做出诊断之后,也可能获得有价值的线索,以解决迄今为止仍然未知的特发性缺血性坏死的病因。