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体外冲击波疗法对手部烧伤所致肥厚性瘢痕的临床效用:一项前瞻性、随机、双盲研究

Clinical Utility of Extracorporeal Shock Wave Therapy on Hypertrophic Scars of the Hand Caused by Burn Injury: A Prospective, Randomized, Double-Blinded Study.

作者信息

Joo So Young, Lee Seung Yeol, Cho Yoon Soo, Seo Cheong Hoon

机构信息

Department of Rehabilitation Medicine, Hangang Sacred Heart Hospital, College of Medicine Hallym University, Seoul 07247, Korea.

Department of Physical Medicine and Rehabilitation, College of Medicine, Soonchunhyang University Hospital, Bucheon 14584, Korea.

出版信息

J Clin Med. 2020 May 7;9(5):1376. doi: 10.3390/jcm9051376.

Abstract

Postburn hypertrophic scarring is a common complication in burn injuries to the hands, often associated with impaired hand function. We evaluated the effects of extracorporeal shock wave therapy (ESWT), compared to a sham stimulation therapy, on hypertrophic scars of the hand caused by burn injury and investigated its effects on hand function. This was a double-blinded, randomized, controlled trial of 48 patients with a burn to their dominant right hand. The parameters of ESWT were as follows: energy flux density, 0.05-0.30 mJ/mm; frequency, 4 Hz; 1000 to 2000 impulses per treatment; four treatments, once a week for four weeks. The outcomes measured were as follows: a 10-point visual analogue scale pain score; Vancouver scar scale for scar vascularity, height, pliability and pigmentation; ultrasound measurement of scar thickness; Jebsen-Taylor hand function test; grip strength; Perdue pegboard test; and the Michigan hand outcomes questionnaire. The change in the score from baseline to post-treatment was compared between the two groups. ESWT improved the pain score ( = 0.001), scar thickness ( = 0.018), scar vascularity ( = 0.0015), and improved hand function (simulated card-turning, = 0.02; picking up small objects, = 0.004). The other measured outcomes were not different between the two groups. ESWT is effective in decreasing pain, suppressing hypertrophic scarring, and improving hand function.

摘要

烧伤后增生性瘢痕是手部烧伤常见的并发症,常伴有手部功能受损。我们评估了体外冲击波疗法(ESWT)与假刺激疗法相比,对烧伤所致手部增生性瘢痕的影响,并研究其对手部功能的作用。这是一项双盲、随机、对照试验,纳入48例右手优势烧伤患者。ESWT的参数如下:能量通量密度,0.05 - 0.30 mJ/mm;频率,4 Hz;每次治疗1000至2000次脉冲;共治疗4次,每周1次,持续4周。测量的结果如下:10分视觉模拟量表疼痛评分;温哥华瘢痕量表评估瘢痕的血管分布、高度、柔韧性和色素沉着;超声测量瘢痕厚度;Jebsen - Taylor手部功能测试;握力;Perdue钉板测试;以及密歇根手部结果问卷。比较两组从基线到治疗后的评分变化。ESWT改善了疼痛评分(P = 0.001)、瘢痕厚度(P = 0.018)、瘢痕血管分布(P = 0.0015),并改善了手部功能(模拟翻牌,P = 0.02;捡起小物体,P = 0.004)。两组之间其他测量结果无差异。ESWT在减轻疼痛、抑制增生性瘢痕形成和改善手部功能方面有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6080/7290924/b8d061cb61a4/jcm-09-01376-g001.jpg

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