温伯格法则在东佛兰德前瞻性双胞胎调查（EFPTS）中的有效性。
The validity of Weinberg's rule in the East Flanders Prospective Twin Survey (EFPTS).
作者信息
Vlietinck R, Derom C, Derom R, Van den Berghe H, Thiery M
机构信息
Department of Human Biology, Catholic University of Leuven, Belgium.
出版信息
Acta Genet Med Gemellol (Roma). 1988;37(2):137-41. doi: 10.1017/s0001566000004049.
Most population studies of twins estimate the number of monozygotic (MZ) and dizygotic (DZ) pairs by Weinberg's differential rule. This rule assumes that within the DZ twins the numbers of unlike-sexed (U) and like-sexed (L) twins are equal. The literature on the validity of Weinberg's rule is still controversial. In this prospective population-based study (EFPTS) of 2,589 twin pairs, of whom 2,577 were of known zygosity and placentation, the estimates of Weinberg's rule agree well with the results of direct zygosity determination.
大多数双胞胎群体研究通过温伯格差异法则来估算同卵双胞胎（MZ）和异卵双胞胎（DZ）的数量。该法则假定在异卵双胞胎中，性别不同的（U）和性别相同的（L）双胞胎数量相等。关于温伯格法则有效性的文献仍存在争议。在这项基于人群的前瞻性研究（EFPTS）中，共有2589对双胞胎，其中2577对的合子性和胎盘情况已知，温伯格法则的估算结果与直接合子性测定的结果非常吻合。
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