单次图像引导机器人立体定向放射外科治疗与颈静脉球瘤的生活质量
Single-session image-guided robotic radiosurgery and quality of life for glomus jugulare tumors.
作者信息
Ehret Felix, Kufeld Markus, Fürweger Christoph, Haidenberger Alfred, Schichor Christian, Tonn Jörg-Christian, Muacevic Alexander, Hempel John-Martin
机构信息
European Cyberknife Center, Munich, Germany.
Department of Stereotaxy and Functional Neurosurgery, Center for Neurosurgery, University Hospital Cologne, Cologne, Germany.
出版信息
Head Neck. 2020 Sep;42(9):2421-2430. doi: 10.1002/hed.26231. Epub 2020 May 12.
BACKGROUND
Limited data are available on the efficacy and impact on the quality of life (Qol) of single-session image-guided robotic radiosurgery (RRS) for glomus jugulare tumors (GJTs). This study investigates the role of RRS in the management of GJTs and reviews the RRS literature.
METHODS
We analyzed 53 GJT patients treated with RRS to evaluate the safety, local control, clinical outcome, and Qol assessed by the SF12v2.
RESULTS
The local control was 98% at a median follow-up of 38 months. The median tumor volume was 4.3 cc and tumors were treated with a median dose of 16.5 Gy. At the last follow-up, 35 patients had recovered from their symptoms or experienced symptom improvement. Qol analyses showed no significant decline while bodily pain significantly decreased.
CONCLUSIONS
RRS is a safe and efficient tool for the treatment of GJTs. Qol of patients after treatment is stable and tends to improve over time.
背景
关于单疗程图像引导机器人放射外科手术（RRS）治疗颈静脉球瘤（GJT）的疗效及对生活质量（Qol）的影响，现有数据有限。本研究探讨了RRS在GJT治疗中的作用，并对RRS相关文献进行了综述。
方法
我们分析了53例接受RRS治疗的GJT患者，以评估安全性、局部控制情况、临床结局以及通过SF12v2评估的生活质量。
结果
中位随访38个月时，局部控制率为98%。中位肿瘤体积为4.3立方厘米，肿瘤接受的中位剂量为16.5 Gy。在最后一次随访时，35例患者症状已缓解或症状有所改善。生活质量分析显示无显著下降，而身体疼痛显著减轻。
结论
RRS是治疗GJT的一种安全有效的工具。治疗后患者的生活质量稳定，且随时间推移有改善趋势。
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