Hatron P Y, Wallaert B, Gaudy D, Bauters F, Gosselin B, Devulder B
Rev Med Interne. 1985 Jan;6(1):9-12. doi: 10.1016/s0248-8663(85)80071-0.
The authors report the case of a woman with Löfgren's syndrome who developed renal failure associated with abnormalities of acidification and concentration of the urine. In the absence of a phosphate-calcium metabolic disturbance, these signs were attributed to a granulomatous interstitial nephropathy demonstrated on renal biopsy. These abnormalities regressed completely with steroid therapy. Secondary renal failure due to an isolated granulomatous interstitial nephropathy is exceptionally rare in sarcoidosis and has never been previously reported in Löfgren's syndrome.
作者报告了一例患有 Löfgren 综合征的女性病例，该患者出现了与尿液酸化和浓缩异常相关的肾衰竭。在不存在磷钙代谢紊乱的情况下，这些体征归因于肾活检显示的肉芽肿性间质性肾炎。这些异常在接受类固醇治疗后完全消退。由孤立性肉芽肿性间质性肾炎引起的继发性肾衰竭在结节病中极为罕见，此前从未在 Löfgren 综合征中报道过。
