Wang Bo, Zhang Xinghua, Jiang Wenyang, Huang Jie, Chen Jingyu, Kreisel Daniel, Danguilan Jose Luis J, Hsin Michael, Lin Huiqing
Department of Thoracic Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Department of Thoracic Surgery, Nanjing Medical University, Affiliated Wuxi People's Hospital, Wuxi 214000, China.
J Thorac Dis. 2020 Apr;12(4):1588-1594. doi: 10.21037/jtd.2020.02.28.
Kartagener syndrome (KS) is an autosomal recessive disorder characterized by situs inversus, paranasal sinusitis and bronchiectasis. We report the successful use of double lung transplant (DLTx) to treat end-stage KS. A 49-year-old Han woman was admitted to Renmin Hospital (Wuhan University, China) in September 2017 with a ≥15 year history of chronic productive cough that had worsened during the past year. Clinical examination and imaging investigations revealed respiratory failure and situs inversus consistent with KS. The patient was successfully treated with DLTx involving bilateral bronchial anastomoses. DLTx is a feasible treatment option for end-stage KS.
卡塔格内综合征（KS）是一种常染色体隐性疾病，其特征为内脏转位、鼻窦炎和支气管扩张。我们报告了成功使用双肺移植（DLTx）治疗终末期KS的病例。一名49岁的汉族女性于2017年9月入住武汉大学人民医院，有≥15年的慢性咳痰病史，且在过去一年病情加重。临床检查和影像学检查显示呼吸衰竭及与KS相符的内脏转位。该患者通过涉及双侧支气管吻合术的DLTx获得成功治疗。DLTx是终末期KS的一种可行治疗选择。
