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2019冠状病毒病与心血管疾病。范围综述研究。

COVID-19 and Cardiovascular diseases. Scoping review study.

作者信息

Yahia Faten, Zakhama Lilia, Ben Abdelaziz Ahmed

出版信息

Tunis Med. 2020 Apr;98(4):283-294.

Abstract

BACKGROUND

Many patients with COVID-19 have pre-existing cardiovascular (CV) co-morbidities or develop acute heart damage during the course of the disease.

OBJECTIVES

To study the risk of COVID-19 infection in the presence of preexisting CV diseases and to describe new CV manifestations during COVID-19.

METHODS

A "scoping review" was carried out via PubMed, to synthesize the results of research currently published on this subject.

RESULTS

Patients with cardiovascular disease were at greater risk of developing COVID-19, especially in its severe form. These patients were five to ten times more at risk of death. Cardiac manifestations, de novo, were dominated by acute myocardial damage, defined by a significant elevation of cardiac troponins. These occurred in 7 to 17% of hospitalized patients. The presence of a new heart lesion in patients with COVID-19 was consistently associated with a poor prognosis.

CONCLUSION

Given the enormous cardiovascular challenge posed by the COVID-19 pandemic and the prognostic impact of heart damage, additional research at a high level of evidence will be necessary.

摘要

背景

许多新冠肺炎患者存在心血管合并症,或在疾病过程中出现急性心脏损伤。

目的

研究存在心血管疾病时感染新冠肺炎的风险,并描述新冠肺炎期间新出现的心血管表现。

方法

通过PubMed进行“范围综述”,以综合当前发表的关于该主题的研究结果。

结果

心血管疾病患者感染新冠肺炎的风险更高,尤其是重症形式。这些患者的死亡风险高出五到十倍。新出现的心脏表现主要为急性心肌损伤,表现为心肌肌钙蛋白显著升高。这在7%至17%的住院患者中出现。新冠肺炎患者出现新的心脏病变始终与预后不良相关。

结论

鉴于新冠肺炎大流行带来的巨大心血管挑战以及心脏损伤对预后的影响,有必要开展更多具有高证据水平的研究。

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