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与胰腺腺泡细胞癌相关的骨髓瘤样管型肾病

Myeloma-like cast nephropathy associated with acinar cell carcinoma of the pancreas.

作者信息

Reducka K, Gardiner G W, Sweet J, Vandenbroucke A, Bear R

机构信息

Department of Pathology, St. Michael's Hospital, Ont., Canada.

出版信息

Am J Nephrol. 1988;8(5):421-4. doi: 10.1159/000167629.

Abstract

Obstruction of renal collecting tubules by protein cats inciting a giant cell reaction is usually characteristic of myeloma cast nephropathy. Rarely other causes of proteinuria may result in a similar morphology. We report a rare case of 'myeloma-like' tubular casts in the kidney of a patient who was subsequently found at autopsy to have acinar cell carcinoma of the pancreas with peritoneal carcinomatosis. Only two similar reports could be found in the English literature.

摘要

蛋白质管型阻塞肾集合管并引发巨细胞反应通常是骨髓瘤管型肾病的特征。很少有其他蛋白尿原因会导致类似的形态学表现。我们报告了一例罕见病例,患者肾脏中出现“骨髓瘤样”肾小管管型,尸检时发现其患有胰腺腺泡细胞癌并伴有腹膜癌转移。在英文文献中仅能找到两篇类似报告。

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