Roy Pritam Kumar, Binks Bernard P, Fujii Syuji, Shoval Shraga, Bormashenko Edward
Chemical Engineering Department, Engineering Faculty, Ariel University, P.O.B. 3, 407000 Ariel, Israel.
Department of Chemistry and Biochemistry, University of Hull, Hull HU6 7RX, U.K.
J Phys Chem Lett. 2020 Jun 4;11(11):4279-4285. doi: 10.1021/acs.jpclett.0c01230. Epub 2020 May 13.
A model macroscopic system imitating the entry of viruses into living cells is suggested. The system represents the contact of a composite (core-shell) liquid marble with hydrophobic/hydrophilic particles. Composite liquid marbles are water droplets coated with silicone oil armored with nanometer-sized hydrophobic particles serving as an interfacial model of a living cell. Composite marbles absorbed hydrophilic polymer particles but prevented hydrophobic particles from entering their core. Swallowing of hydrophilic particles by composite marbles resembles the penetration of viruses into living cells. The interfacial mechanism of absorption is suggested.
提出了一种模拟病毒进入活细胞过程的宏观模型系统。该系统是复合（核壳）液滴与疏水/亲水颗粒的接触。复合液滴是包裹有硅油的水滴，硅油上附着纳米级疏水颗粒，作为活细胞的界面模型。复合液滴吸收亲水聚合物颗粒，但阻止疏水颗粒进入其核心。复合液滴吞噬亲水颗粒类似于病毒进入活细胞的过程。提出了吸收的界面机制。
