Houndji Mahugnon A B, Imorou Toko Ibrahim, Guedegba Léa, Yacouto Edith, Agbohessi Prudencio T, Mandiki Syaghalirwa N M, Scippo Marie-Louise, Kestemont Patrick
Research Laboratory in Aquaculture and Aquatic Ecotoxicology (LaRAEAq), Department of Animal Production, Faculty of Agronomy, University of Parakou, Parakou, Benin.
Research Unit in Environmental and Evolutionary Biology (URBE), Institute of Life, Earth & Environment (ILEE), University of Namur, Namur, Belgium.
J Environ Sci Health B. 2020;55(7):669-676. doi: 10.1080/03601234.2020.1763712. Epub 2020 May 12.
This study was designed to evaluate the acute toxicity of acetamiprid (neonicotinoid) and lambda-cyhalothrin (pyrethroid), individually and mixtures (Act-LCh mixture and Acer 35 EC®, 15 g/L of acetamiprid and 20 g/L of lambda-cyhalothrin) in African catfish juveniles (3.35 ± 0.75 g). The tests were conducted in the laboratory under semi-static conditions according to OECD Guideline 203. Mixture toxicity effects as a function of lethal concentrations were assessed using the additive index (AI) method. Acetamiprid with 96 h-LC = 265.7 ppm can be considered to be nontoxic for this species. However, lambda-cyhalothrin was highly toxic to with 96 h-LC = 0.00083 ppm. Acer 35 EC was less toxic (96 h-LC = 0.21 ppm) than the Act-LCh mixture (96 h-LC = 0.043 ppm). Marked changes indicating nervous system damage were also recorded. An antagonistic effect was shown for lethal concentrations leading to 5 to 15% mortality in 96 hours (96 h-LC) while an additive effect was obtained for the 96 h-LC. The results indicate that ecological risk assessment of these molecules in aquatic environments should consider their contamination levels. Moreover, particular attention to behavior changes related to their neurotoxicity is recommended for additional monitoring of the negative effects of these insecticides.
本研究旨在评估啶虫脒（新烟碱类）和高效氯氟氰菊酯（拟除虫菊酯类）单独及混合使用（啶虫脒-高效氯氟氰菊酯混合物和Acer 35 EC®，其中啶虫脒含量为15 g/L，高效氯氟氰菊酯含量为20 g/L）对非洲鲶鱼幼鱼（体重3.35±0.75 g）的急性毒性。试验依据经合组织准则203在实验室半静态条件下进行。使用相加指数（AI）法评估作为致死浓度函数的混合物毒性效应。啶虫脒的96小时半数致死浓度（96 h-LC）为265.7 ppm，可认为对该物种无毒。然而，高效氯氟氰菊酯对其毒性极高，96小时半数致死浓度为0.00083 ppm。Acer 35 EC的毒性（96小时半数致死浓度为0.21 ppm）低于啶虫脒-高效氯氟氰菊酯混合物（96小时半数致死浓度为0.043 ppm）。还记录到表明神经系统损伤的明显变化。在导致96小时内5%至15%死亡率的致死浓度下显示出拮抗作用，而在96小时半数致死浓度下则呈现相加作用。结果表明，对这些分子在水生环境中的生态风险评估应考虑其污染水平。此外，建议特别关注与它们的神经毒性相关的行为变化，以便对这些杀虫剂的负面影响进行额外监测。
