Clemmensen O J, Krogh J, Petri M
Department of Pathology, Sundby Hospital, Copenhagen, Denmark.
Am J Dermatopathol. 1988 Apr;10(2):104-8. doi: 10.1097/00000372-198804000-00002.
Histologic examination of the prepuces removed from 78 consecutive patients with phimosis was performed during a 2-year period. In 15 cases (14.2%), the typical changes of lichen sclerosus et atrophicus (LSA) were found. A different, distinct histologic pattern of fibrosis was noticed in six patients (7.7%). Clinically, the two conditions were indistinguishable and presented as severe, nonretractable phimosis. The largest group of the patients (46.2%) had histologically normal prepuces, but clinically they too had severe phimosis. Since phimosis especially in young boys may regress spontaneously, and since on the other hand LSA may evolve into squamous cell carcinoma, we conclude that treatment of phimosis should be planned according to its histologic pattern and not according to its monotonous clinical appearance.
在两年期间，对连续78例包茎患者切除的包皮进行了组织学检查。15例（14.2%）发现了硬化性苔藓萎缩性病变（LSA）的典型变化。在6例患者（7.7%）中注意到一种不同的、独特的纤维化组织学模式。临床上，这两种情况无法区分，均表现为严重的、不可退缩的包茎。最大的一组患者（46.2%）包皮组织学正常，但临床上他们也患有严重包茎。由于包茎尤其是在小男孩中可能会自发消退，而另一方面LSA可能会演变成鳞状细胞癌，我们得出结论，包茎的治疗应根据其组织学模式而不是其单一的临床表现来规划。
