Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
Department of Occupational Health Engineering, Faculty of Health, Tabriz University of Medical Sciences, Tabriz, Iran.
J Environ Sci Health C Toxicol Carcinog. 2020;38(1):61-90. doi: 10.1080/26896583.2020.1715713. Epub 2020 Mar 18.
Today, due to the growth of industries and spread of the use of various instruments and devices that produce high noise levels, it is necessary to pay more attention to the effects of exposure to noise on organs and tissues in the body. The importance of the immune system in fighting external and pathogenic factors has raised the need to consider external factors (such as harmful physical factors) and make efforts to avoid producing them. In this systematic review, 811 potentially relevant studies were found in Google Scholar, PubMed, and Web of Science databases, of which 32 different English-written articles were included in the study. The method of searching and systematically reviewing articles was based on the assessment tool of the multiple systematic reviews (AMSTAR) method. The results of this study suggested that noise could affect the function of the immune system and its components by affecting other systems and organs of the body, including the central nervous system, auditory system, circulatory system, and endocrine gland. Moreover, it can be hypothesized that noise affects immune system by producing the NADPH oxidase (Nox) and reactive oxygen species (ROS).
如今，由于各行业的发展以及各种产生高强度噪声的仪器和设备的广泛使用，有必要更加关注人们接触噪声对体内器官和组织的影响。免疫系统在抵御外来和致病因素方面的重要性使得人们需要考虑外部因素（如有害的物理因素），并努力避免这些因素的产生。在这项系统性综述中，在 Google Scholar、PubMed 和 Web of Science 数据库中发现了 811 项潜在相关研究，其中包括 32 篇不同的英文文章。文章检索和系统性综述的方法是基于多系统性综述评估工具（AMSTAR）方法。这项研究的结果表明，噪声可以通过影响身体的其他系统和器官，包括中枢神经系统、听觉系统、循环系统和内分泌腺，来影响免疫系统及其组成部分的功能。此外，可以假设噪声通过产生 NADPH 氧化酶（Nox）和活性氧（ROS）来影响免疫系统。
