Division of Cardiovascular Medicine, Michigan Medicine, University of Michigan, Ann Arbor, MI, USA.
J Hum Hypertens. 2020 Sep;34(9):609-616. doi: 10.1038/s41371-020-0350-4. Epub 2020 May 12.
Coronary artery calcium (CAC) is increased by high blood pressure (BP), predicts new-onset hypertension, and is a powerful predictor of atherosclerotic cardiovascular disease events in patients with and without hypertension. Unlike other diseases (e.g., hypercholesterolemia), the clinical use of CAC scoring to personalize the treatment of high BP has not received much attention and therefore remains less well defined. Herein, we provide an updated review of studies investigating the relationship between CAC and BP. Finally, we propose a clinical algorithm to incorporate CAC into hypertension management, with a focus on its potential value in tailoring the timing of medication therapy and in helping to personalize BP goals.
冠状动脉钙(CAC)可因高血压(BP)而增加,可预测新发高血压,并可有力预测高血压和无高血压患者的动脉粥样硬化性心血管疾病事件。与其他疾病(如高胆固醇血症)不同,CAC 评分在高血压治疗中的个体化应用尚未受到太多关注,因此定义仍不明确。本文提供了一项关于 CAC 与 BP 关系的研究的最新综述。最后,我们提出了一种将 CAC 纳入高血压管理的临床算法,重点探讨其在调整药物治疗时机和帮助个性化 BP 目标方面的潜在价值。