Suppr超能文献

一名患有肿瘤性双重病变患者的神经内分泌肿瘤中氟西克洛维的意外蓄积

Incidental Accumulation of Fluciclovine in Neuroendocrine Tumour in a Patient with Oncological Duplicity.

作者信息

Balážová Zuzana, Černý Igor, Vyškovský Petr

机构信息

Department of Radiology and Nuclear Medicine, University Hospital Brno, Brno, Czechia.

Faculty of Medicine, Masaryk University, Brno, Czechia.

出版信息

Case Rep Oncol. 2020 Apr 21;13(1):431-435. doi: 10.1159/000506829. eCollection 2020 Jan-Apr.

Abstract

18F-fluciclovine is a PET radiopharmaceutical used for the detection of recurrent prostate cancer in adult men after primary curative treatment with suspicion of recurrence based on elevated prostate-specific antigen level. Several incidental uptakes of 18F-fluciclovine in other tumour types have been described in the literature so far - in breast cancer, hepatocellular carcinoma, and malignant melanoma. Our case report presents a patient with oncological duplicity (prostate gland carcinoma and newly diagnosed neuroendocrine tumour) and with accumulation of fluciclovine in pathologically proved neuroendocrine tumour, later imagined also by octreotide SPECT/CT. To our knowledge, this is the first case of fluciclovine accumulated in a neuroendocrine tumour described in the literature.

摘要

18F-氟西克洛维是一种正电子发射断层扫描(PET)放射性药物,用于在成年男性接受原发性根治性治疗后,基于前列腺特异性抗原水平升高怀疑复发时检测复发性前列腺癌。迄今为止,文献中已描述了18F-氟西克洛维在其他肿瘤类型中的一些意外摄取情况——在乳腺癌、肝细胞癌和恶性黑色素瘤中。我们的病例报告介绍了一名患有肿瘤双重性(前列腺癌和新诊断的神经内分泌肿瘤)的患者,氟西克洛维在经病理证实的神经内分泌肿瘤中积聚,后来奥曲肽单光子发射计算机断层扫描/计算机断层扫描(SPECT/CT)也显示了这一情况。据我们所知,这是文献中描述的首例氟西克洛维在神经内分泌肿瘤中积聚的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4458/7204768/13e9ddb96e41/cro-0013-0431-g01.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验