Balážová Zuzana, Černý Igor, Vyškovský Petr
Department of Radiology and Nuclear Medicine, University Hospital Brno, Brno, Czechia.
Faculty of Medicine, Masaryk University, Brno, Czechia.
Case Rep Oncol. 2020 Apr 21;13(1):431-435. doi: 10.1159/000506829. eCollection 2020 Jan-Apr.
18F-fluciclovine is a PET radiopharmaceutical used for the detection of recurrent prostate cancer in adult men after primary curative treatment with suspicion of recurrence based on elevated prostate-specific antigen level. Several incidental uptakes of 18F-fluciclovine in other tumour types have been described in the literature so far - in breast cancer, hepatocellular carcinoma, and malignant melanoma. Our case report presents a patient with oncological duplicity (prostate gland carcinoma and newly diagnosed neuroendocrine tumour) and with accumulation of fluciclovine in pathologically proved neuroendocrine tumour, later imagined also by octreotide SPECT/CT. To our knowledge, this is the first case of fluciclovine accumulated in a neuroendocrine tumour described in the literature.
18F-氟西克洛维是一种正电子发射断层扫描（PET）放射性药物，用于在成年男性接受原发性根治性治疗后，基于前列腺特异性抗原水平升高怀疑复发时检测复发性前列腺癌。迄今为止，文献中已描述了18F-氟西克洛维在其他肿瘤类型中的一些意外摄取情况——在乳腺癌、肝细胞癌和恶性黑色素瘤中。我们的病例报告介绍了一名患有肿瘤双重性（前列腺癌和新诊断的神经内分泌肿瘤）的患者，氟西克洛维在经病理证实的神经内分泌肿瘤中积聚，后来奥曲肽单光子发射计算机断层扫描/计算机断层扫描（SPECT/CT）也显示了这一情况。据我们所知，这是文献中描述的首例氟西克洛维在神经内分泌肿瘤中积聚的病例。
