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以小转子无创伤性撕脱骨折为表现的转移性非小细胞肺癌初步报告

Preliminary Presentation of Metastatic Non-Small Cell Carcinoma of the Lung as Atraumatic Avulsion Fracture of the Lesser Trochanter.

作者信息

Creissen Adam, Rajeev Aysha, Jain Kumud, Banaszkiewicz Paul

机构信息

Orthopaedic Department, Queen Elizabeth Hospital, Gateshead, United Kingdom.

Clinical Pathology, Queen Elizabeth Hospital, Gateshead, United Kingdom.

出版信息

Case Rep Oncol. 2020 Apr 21;13(1):436-441. doi: 10.1159/000506451. eCollection 2020 Jan-Apr.

DOI:10.1159/000506451
PMID:32399013
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7204840/
Abstract

Traumatic avulsion fractures of the lesser trochanter are usually seen along with fractures of the proximal femur and with young adolescents involved in high-intensity sporting injuries. Atraumatic isolated lesser trochanter avulsion in adults are most commonly associated with malignancy. We describe a case of a female in her sixties who was previously fit and healthy with no systemic illness and no history of trauma presenting with groin pain. The X-ray demonstrated an isolated lesser trochanter avulsion fracture. Further imaging including MRI and a staging CT scan of the neck, chest, abdomen and pelvis revealed a pulmonary tumour. Biopsy later confirmed this as a non-small cell carcinoma of the lung. At the time of publication, she had been started on palliative chemotherapy (afatinib) with encouraging results.

摘要

小转子创伤性撕脱骨折通常与股骨近端骨折同时出现,多见于参与高强度运动损伤的青少年。成人非创伤性孤立性小转子撕脱最常见于恶性肿瘤。我们报告一例60多岁女性病例,她既往身体健康,无全身性疾病,无外伤史,现因腹股沟疼痛就诊。X线显示孤立性小转子撕脱骨折。进一步的影像学检查,包括MRI以及颈部、胸部、腹部和骨盆的分期CT扫描,发现肺部有肿瘤。活检后来证实为肺非小细胞癌。在发表本文时,她已开始接受姑息化疗(阿法替尼),效果令人鼓舞。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f8b/7204840/f52511b22b98/cro-0013-0436-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f8b/7204840/c0b127d631ef/cro-0013-0436-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f8b/7204840/1cc04c1eb98a/cro-0013-0436-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f8b/7204840/05ac6ced67b5/cro-0013-0436-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f8b/7204840/f52511b22b98/cro-0013-0436-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f8b/7204840/c0b127d631ef/cro-0013-0436-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f8b/7204840/1cc04c1eb98a/cro-0013-0436-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f8b/7204840/05ac6ced67b5/cro-0013-0436-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f8b/7204840/f52511b22b98/cro-0013-0436-g04.jpg

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本文引用的文献

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Isolated Spontaneous Atraumatic Avulsion of Lesser Trochanter of Femur-A Pathognomonic Sign of Malignancy in Adults? A Case Report and Review of Literature.成人股骨小转子孤立性自发性无创伤性撕脱——恶性肿瘤的特征性体征?一例病例报告及文献复习
J Orthop Case Rep. 2017 Nov-Dec;7(6):16-19. doi: 10.13107/jocr.2250-0685.930.
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Nonpathological Lesser Trochanter Fracture in Adult: Case Report and Brief Review of Literature.成人非病理性小转子骨折:病例报告及文献简要综述
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Breast cancer bone metastases: an orthopedic emergency.乳腺癌骨转移:一种骨科急症。
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Orthop Traumatol Surg Res. 2011 Apr;97(2):217-20. doi: 10.1016/j.otsr.2010.11.005. Epub 2011 Feb 26.
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Isolated lesser trochanter fracture associated with leukemia.孤立性小转子骨折合并白血病
Am J Orthop (Belle Mead NJ). 2009 Mar;38(3):E56-8.
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Atraumatic avulsion of the lesser trochanter as an indicator of tumour infiltration.小转子无创伤性撕脱作为肿瘤浸润的指标。
Eur Radiol. 2006 Feb;16(2):512-4. doi: 10.1007/s00330-005-2675-3. Epub 2005 Feb 9.
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Bone metastases revealing primary tumors. Comparison of two series separated by 30 years.揭示原发性肿瘤的骨转移。相隔30年的两个系列的比较。
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FRACTURES OF THE APOPHYSES IN ADOLESCENT ATHLETES.青少年运动员的骨骺骨折
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