Suppr超能文献

冻结现象不止于步态:帕金森病中一例排尿冻结的病例报告

Freezing More than Gait: A Case Report of Freezing of Urination (FOU) in Parkinson's Disease.

作者信息

Xu Mengyuan, Chen Tao, Yang Caifei, Meng Xu, Peng Qingyun, Lei Xiaoguang

机构信息

Department of Neurology, Kunming Medical University, Kunming 650000, China.

Department of Neurology, First Affiliated Hospital of Kunming Medical University, Kunming 650000, China.

出版信息

Parkinsons Dis. 2020 Jan 21;2020:5190703. doi: 10.1155/2020/5190703. eCollection 2020.

Abstract

Freezing of gait (FOG) is a disabling phenomenon that is described by patients with Parkinson's disease (PD). Not only gait may be involved in the freezing phenomenon, but also some nonmotor symptoms, such as freezing of urination (FOU) in this case. The characters of urinary dysfunctions in this case resemble "off" freezing: (1) abrupt difficulty in starting or continuing in urination; (2) the urinary dysfunctions fluctuated with medication state; and (3) the urinary dysfunctions could be alleviated dramatically by an external cueing. Urinary dysfunctions in this patient (and maybe more PD patients) are associated not only with the classical "nonmotor symptoms" but also the freezing phenomenon. FOU could be a part of the spectrum of freezing symptoms. The subtypes of the freezing phenomenon will shed light on the PD pathophysiology and clinical treatment.

摘要

冻结步态(FOG)是帕金森病(PD)患者描述的一种致残现象。不仅步态可能参与冻结现象,在这种情况下一些非运动症状也会出现,比如排尿冻结(FOU)。该病例中排尿功能障碍的特征类似于“关期”冻结:(1)排尿起始或持续突然困难;(2)排尿功能障碍随药物状态波动;(3)外部提示可显著缓解排尿功能障碍。该患者(可能更多PD患者)的排尿功能障碍不仅与典型的“非运动症状”有关,还与冻结现象有关。排尿冻结可能是冻结症状谱的一部分。冻结现象的亚型将为帕金森病的病理生理学和临床治疗提供线索。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7608/7201630/8fa4eb9facb0/PD2020-5190703.001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验