Deckers Eric A, Louwman Marieke Wj, Kruijff Schelto, Hoekstra Harald J
Department of Surgical Oncology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Netherlands Comprehensive Cancer Organisation (IKNL), Utrecht, The Netherlands.
Melanoma Manag. 2020 Mar 30;7(1):MMT38. doi: 10.2217/mmt-2019-0018.
To investigate implementation of the seventh American Joint Committee on Cancer melanoma staging with sentinel lymph node biopsy (SLNB) and associations with socioeconomic status (SES).
PATIENTS & METHODS: Data from The Netherlands Cancer Registry on patient and tumor characteristics were analyzed for all stage IB-II melanoma cases diagnosed 2010-2016, along with SES data from The Netherlands Institute for Social Research.
The proportion of SLNB-staged patients increased from 40% to 65% (p < 0.001). Multivariate analysis showed that being female, elderly, or having head-and-neck disease reduced the likelihood of SLNB staging.
SLNB staging increased by 25% during the study period but lagged among elderly patients and those with head-and-neck melanoma. In The Netherlands, SES no longer affects SLNB staging performance.
研究美国癌症联合委员会第七版黑色素瘤分期系统在前哨淋巴结活检（SLNB）中的实施情况及其与社会经济地位（SES）的关联。
分析了荷兰癌症登记处2010 - 2016年诊断的所有IB - II期黑色素瘤病例的患者和肿瘤特征数据，以及荷兰社会研究所的社会经济地位数据。
接受SLNB分期的患者比例从40%增至65%（p < 0.001）。多因素分析显示，女性、老年患者或患有头颈部疾病会降低SLNB分期的可能性。
在研究期间，SLNB分期增加了25%，但在老年患者和头颈部黑色素瘤患者中滞后。在荷兰，社会经济地位不再影响SLNB分期表现。
