Suppr超能文献

值得思考的问题:针对严重通气衰竭罕见病因的饮食干预

Food for Thought: Dietary Intervention in a Rare Cause of Severe Ventilatory Failure.

作者信息

Yung Henry, Sharma Keshav, Flowers William, Marquette Malcolm, Starace Laura, Sander Clare, Burnstein Rowan, Herre Jurgen

机构信息

Respiratory Department, Cambridge University Hospitals, Cambridge, UK.

Rayne Institute, University College London, London, UK.

出版信息

Eur J Case Rep Intern Med. 2020 Mar 26;7(5):001523. doi: 10.12890/2020_001523. eCollection 2020.

Abstract

UNLABELLED

Plastic bronchitis is a rare condition characterised by endobronchial cast formation. We report the case of a 53-year-old women who deteriorated following an elective bronchoscopy procedure. She developed refractory ventilatory failure and required repeated bronchoscopy, which identified thick tenacious casts as the cause of her airway compromise. She did not respond to conventional therapies including endoscopic clearance, mucolytic therapy and nebulised tissue plasminogen activator (TPA). Total parenteral nutrition and a fat-free enteral diet were instituted while the patient was on extracorporeal membrane oxygenation (ECMO), which led to substantial improvement in her condition and demonstrated the importance of dietary strategies in this case.

LEARNING POINTS

Plastic bronchitis can rarely present in adults with acute ventilatory failure and life-threatening airway obstruction.Although there are no established guidelines on management, dietary intervention (e.g., a fat-free diet) should be strongly considered as a therapeutic option.Extracorporeal membrane oxygenation (ECMO) is feasible and should be considered in plastic bronchitis with airway compromise.

摘要

未标注

塑料支气管炎是一种以支气管内铸型形成为特征的罕见病症。我们报告了一例53岁女性患者,她在择期支气管镜检查术后病情恶化。她出现难治性通气衰竭,需要反复进行支气管镜检查,结果发现黏稠的铸型是其气道阻塞的原因。她对包括内镜清除、黏液溶解疗法和雾化组织型纤溶酶原激活剂(TPA)在内的传统治疗均无反应。在患者接受体外膜肺氧合(ECMO)治疗期间,采用了全胃肠外营养和无脂肠内饮食,这使她的病情有了显著改善,并证明了饮食策略在该病例中的重要性。

学习要点

塑料支气管炎在成人中很少表现为急性通气衰竭和危及生命的气道阻塞。尽管目前尚无既定的管理指南,但应强烈考虑饮食干预(如无脂饮食)作为一种治疗选择。体外膜肺氧合(ECMO)是可行的,对于有气道阻塞的塑料支气管炎患者应予以考虑。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ffa/7213828/3386f31e01e7/1523_Fig1.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验