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体外膜肺氧合治疗 Ross 手术后急性塑性支气管炎。

Acute plastic bronchitis after Ross procedure treated with veno-venous extracorporeal membrane oxygenation.

机构信息

Department of Medicine, Internal Medicine and Critical Care Division, Université de Sherbrooke, 3001, 12e Avenue Nord, Sherbrooke, QC, J1H 5N4, Canada.

Department of Surgery, Cardiac Surgery Division, Centre Hospitalier Universitaire de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, Canada.

出版信息

Can J Anaesth. 2022 Feb;69(2):265-268. doi: 10.1007/s12630-021-02148-2. Epub 2021 Dec 2.

Abstract

PURPOSE

Plastic bronchitis is a rare condition characterized by the formation of airway casts occluding the lower respiratory tract. It is described more commonly in children, especially following correction of congenital heart disease. It involves lymphatic abnormalities leading to endobronchial lymph precipitating airway cast formation. When it presents acutely, it can lead to acute airway obstruction, which can be life-threatening. Plastic bronchitis has been rarely described in adults and is potentially underdiagnosed. The purpose of this case report is to emphasize, for the adult anesthesiologist and adult critical care physician, the importance of prompt diagnosis and respiratory support in a case of plastic bronchitis.

CLINICAL FEATURES

A 40-yr-old female with severe aortic stenosis underwent a Ross procedure. The surgery was uneventful, but within two hours of arrival in the intensive care unit, the patient developed severe hypoxemia. Despite attempts to optimize her respiratory status, the patient remained severely hypoxemic, and veno-venous extracorporeal membrane oxygenation (ECMO) was initiated using a percutaneous femoro-femoral cannulation. A bronchoscopy showed bronchial secretions casting the proximal bronchus, suggestive of plastic bronchitis. After numerous bronchoscopies, we were able to clean the airways and wean the ECMO support on postoperative day 3.

CONCLUSION

Plastic bronchitis can present in adult patients and be life-threatening when associated with acute respiratory failure. We report an unusual case of an adult patient treated with veno-venous ECMO for plastic bronchitis following cardiac surgery. Use of ECMO support while providing airway cleaning can be lifesaving in patients with respiratory failure secondary to plastic bronchitis.

摘要

目的

塑型性支气管炎是一种罕见的疾病,其特征是气道铸型形成,阻塞下呼吸道。它在儿童中更为常见,特别是在先天性心脏病矫正后。它涉及淋巴异常导致内支气管淋巴沉淀形成气道铸型。当它急性发作时,可导致急性气道阻塞,危及生命。塑型性支气管炎在成人中很少见,可能被误诊。本病例报告的目的是强调,对于成人麻醉师和成人重症监护医生,及时诊断和呼吸支持对塑型性支气管炎病例的重要性。

临床特征

一名 40 岁女性患有严重的主动脉瓣狭窄,接受了 Ross 手术。手术过程顺利,但在进入重症监护病房的两小时内,患者出现严重的低氧血症。尽管试图优化她的呼吸状况,但患者仍严重低氧血症,启动了经皮股股静脉体外膜氧合(ECMO)。支气管镜检查显示支气管分泌物铸型近端支气管,提示塑型性支气管炎。经过多次支气管镜检查,我们能够清理气道并在术后第 3 天撤下 ECMO 支持。

结论

塑型性支气管炎可发生在成年患者中,并在伴有急性呼吸衰竭时危及生命。我们报告了一例罕见的成年患者,在心脏手术后因塑型性支气管炎接受了股股静脉 ECMO 治疗。在因塑型性支气管炎导致呼吸衰竭的患者中,使用 ECMO 支持同时进行气道清理可以挽救生命。

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