Lorenzo Villalba Noel, Zulfiqar Abrar-Ahmad, Maouche Yasmine, Cordoba Sosa Zaida, Alonso Ortiz Maria Belen, Andres Emmanuel
Service de Médecine Interne, Diabète et Maladies Métaboliques, Hôpitaux Universitaires de Strasbourg, France.
Internal Medicine Department, Fuerteventura General Hospital, Fuerteventura, Spain.
Eur J Case Rep Intern Med. 2020 Mar 30;7(5):001589. doi: 10.12890/2020_001589. eCollection 2020.
We report the case of a 23-year-old woman evaluated for asthenia and lymphocytopenia. Clinical examination was unremarkable but laboratory tests showed the presence of CD4 lymphocytopenia. Secondary causes of CD4 lymphocytopenia were ruled out and a previous diagnosis of idiopathic CD4+ T-cell lymphocytopenia was retained. CD4 lymphocytopenia has persisted for 11 years now but the patient has been clinically asymptomatic.
CD4+ T-cell lymphocytopenia needs to be meticulously evaluated and secondary causes ruled out.The patient has been clinically asymptomatic for 11 years.Measurement of CD4 subsets twice yearly seems to be appropriate.
我们报告了一例23岁女性因乏力和淋巴细胞减少前来评估的病例。临床检查无异常，但实验室检查显示存在CD4淋巴细胞减少。排除了CD4淋巴细胞减少的继发原因，维持先前特发性CD4+ T细胞淋巴细胞减少的诊断。CD4淋巴细胞减少至今已持续11年，但患者临床上无症状。
CD4+ T细胞淋巴细胞减少需要仔细评估并排除继发原因。该患者已临床无症状11年。每年两次检测CD4亚群似乎是合适的。
