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在家烤制肉类或鱼类对成年哮喘患者呼气峰值流速的影响。

Impact of Grilling Meat or Fish at Home on Peak Expiratory Flow Rate in Adults With Asthma.

作者信息

Lee Hyun, Chung Sung Jun, Park Jong Sook, Kim Sungroul, Park Dong Won, Sohn Jang Won, Kim Sang Heon, Park Choon Sik, Yoon Ho Joo

机构信息

Division of Pulmonary Medicine and Allergy, Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.

Allergy and Respiratory Medicine, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.

出版信息

Allergy Asthma Immunol Res. 2020 Jul;12(4):729-737. doi: 10.4168/aair.2020.12.4.729.

Abstract

Grilling, a common cooking method worldwide, can produce more toxic gases than other cooking methods. However, the impact of frequently grilling meat or fish at home on airflow limitation in adult asthma has not been well elucidated. We performed a prospective cohort study of 91 adult patients with asthma enrolled from 2 university hospitals. Of the patients, 39 (42.9%) grilled meat or fish at least once a week and 52 (57.1%) less than once a week. Patients who grilled at least once a week tended to have lower peak expiratory flow rate (PEFR) than those who grilled less than once a week (median, 345.5 L/min; 95% confidence interval [CI], 291.8-423.2 L/min vs. median, 375.1 L/min; 95% CI, 319.7-485.7 L/min; = 0.059). Among patients with severe asthma who received step 4-5 treatment, PEFR was significantly lower in patients who grilled at least once a week compared with those who grilled less than once a week (median, 297.8 L/min; 95% CI, 211.3-357.7 L/min . median, 396.1 L/min; 95% CI, 355.0-489.6 L/min; < 0.001). Our results suggest that the frequency of grilling meat or fish at home may affect PEFR in asthmatic patients, especially those with severe asthma who needed a high level of asthma treatment.

摘要

烧烤是一种在全球范围内普遍使用的烹饪方法,它产生的有毒气体比其他烹饪方法更多。然而,在家中频繁烧烤肉类或鱼类对成年哮喘患者气流受限的影响尚未得到充分阐明。我们对从两家大学医院招募的91名成年哮喘患者进行了一项前瞻性队列研究。在这些患者中,39名(42.9%)每周至少烧烤一次肉类或鱼类,52名(57.1%)每周烧烤次数少于一次。每周至少烧烤一次的患者其呼气峰值流速(PEFR)往往低于每周烧烤次数少于一次的患者(中位数为345.5升/分钟;95%置信区间[CI]为291.8 - 423.2升/分钟,而中位数为375.1升/分钟;95%CI为319.7 - 485.7升/分钟;P = 0.059)。在接受4 - 5级治疗的重度哮喘患者中,每周至少烧烤一次的患者其PEFR显著低于每周烧烤次数少于一次的患者(中位数为297.8升/分钟;95%CI为211.3 - 357.7升/分钟,中位数为396.1升/分钟;95%CI为355.0 - 489.6升/分钟;P < 0.001)。我们的结果表明,在家中烧烤肉类或鱼类的频率可能会影响哮喘患者的PEFR,尤其是那些需要高水平哮喘治疗的重度哮喘患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc4e/7225005/d12d92c789f4/aair-12-729-g001.jpg

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