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越南一例罕见的 致真菌性烧伤创面感染

A Rare Case of Fungal Burn Wound Infection Caused by in Vietnam.

机构信息

Vinh Hospital of Friendship General, Vinh, Nghe An, Vietnam.

National Hospital of Burns, Vietnam Military Medical University, Ha Noi, Vietnam.

出版信息

J Investig Med High Impact Case Rep. 2020 Jan-Dec;8:2324709620912122. doi: 10.1177/2324709620912122.

Abstract

A patient with extensive burn injuries was admitted to the National Hospital of Burns in Hanoi, Vietnam, and diagnosed with fungal wound infection by histological examination of skin biopsy samples. was isolated and identified by analysis of its morphological features and the sequence of the internal transcribed spacer region. The isolation showed in vitro resistant to fluconazole, voriconazole, itraconazole, amphotericin B, and caspofungin. Invasive fusariosis is difficult to treat due to its angioinvasive property and its lacking amenability to treatment with antifungal drugs. This infection is rare and has not been reported so far in Vietnam.

摘要

一名大面积烧伤患者被收入越南河内国家烧伤医院,通过皮肤活检样本的组织学检查诊断为真菌感染性伤口感染。通过分析其形态特征和内部转录间隔区序列对进行了分离和鉴定。分离株在体外对氟康唑、伏立康唑、伊曲康唑、两性霉素 B 和卡泊芬净均有耐药性。侵袭性镰刀菌病由于其血管侵袭性和对抗真菌药物治疗的顺应性差,因此难以治疗。这种感染很少见,迄今为止在越南尚未有报道。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab7b/7223860/7a845031ea8b/10.1177_2324709620912122-fig2.jpg

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