Department of Otolaryngology-Head and Neck Surgery, Taipei Veterans General Hospital, Taipei, Taiwan.
Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan.
Head Neck. 2020 Sep;42(9):2340-2347. doi: 10.1002/hed.26249. Epub 2020 May 13.
Xerostomia is one of the most common long-term adverse effects of radiotherapy for head and neck cancer patients. Contralateral submandibular gland transfer (SMG-T) before radiotherapy was shown to reduce xerostomia compared to pilocarpine. We sought to evaluate a modification of this surgery preserving the ipsilateral facial artery and vein to simplify the SMG-T.
Eighteen patients planned for head and neck intensity modulated radiotherapy to both necks were reviewed. Surgical complications were recorded. The grade of xerostomia was assessed after treatment completion.
There were no minor or major complications resulting from the modified SMG-T. At 24.5-months follow up, the incidence of post-treatment moderate to severe xerostomia was 16.7%. No locoregional recurrence occurred. Only one patient had distant solitary lung metastasis.
The modified SMG-T technique is a practical and effective method to reduce the dose of radiation to the contralateral SMG and limit post-treatment xerostomia.
口干症是头颈部癌症患者放射治疗后最常见的长期不良反应之一。与毛果芸香碱相比，放射治疗前对健侧颌下腺进行转移（SMG-T）可减少口干症。我们试图评估这种手术的改良方法，保留同侧面动脉和静脉，以使 SMG-T 更简单。
回顾了 18 例计划接受颈部强度调制放射治疗的头颈部癌症患者。记录了手术并发症。治疗完成后评估口干症的程度。
改良 SMG-T 无轻微或严重并发症。24.5 个月随访时，治疗后中重度口干症的发生率为 16.7%。无局部区域复发。只有 1 例患者发生远处单发肺转移。
改良 SMG-T 技术是一种实用有效的方法，可以减少对健侧颌下腺的放射剂量，限制治疗后口干症的发生。
