Khaled Yaseer S, Jamil Hassan F, Badi Suleiman H
Servicio de Dermatología y Venereología, Facultad de Medicina, Universidad de Tishreen, Latakia, Siria.
Servicio de Dermatología y Venereología, Facultad de Medicina, Universidad de Tishreen, Latakia, Siria.
Actas Dermosifiliogr (Engl Ed). 2020 Sep;111(7):574-578. doi: 10.1016/j.ad.2019.11.004. Epub 2020 May 13.
Platelet rich plasma is a source of growth factors recently introduced to treat androgenetic alopecia (AGA) with conflicting results. Our aims are to assess the efficacy of platelet rich plasma in increasing hair density in males with AGA, and to investigate a correlation between positive response and each of patient's age and type and duration of AGA.
MATERIALS & METHODS: This before and after study included 30 males with no history of hair treatments for at least 3 months prior to our study. Each patient received 3 injections at one-month intervals. Scalp hair density of each subject was measured manually by a dermatoscope before and following 2 and 6 months of the first intervention. Data were compared to evaluate efficacy.
Hair density was increased by 19.17% following our intervention (172.46±59.04 hairs/cm before treatment to 205.53±68.20 hairs/cm after 6 months) with minimal short-term side effects. Type III vertex was the least responsive pattern and no correlation was observed between positive response and either patient's age or duration of AGA.
Platelet rich plasma injections for men with AGA has a positive effect on hair density.
富血小板血浆是一种生长因子来源，最近被用于治疗雄激素性脱发（AGA），但其结果存在争议。我们的目的是评估富血小板血浆对增加男性AGA患者头发密度的疗效，并研究阳性反应与患者年龄、AGA类型及病程之间的相关性。
这项前后对照研究纳入了30名在我们研究前至少3个月没有进行过头发治疗史的男性。每位患者每隔1个月接受3次注射。在首次干预前以及干预后2个月和6个月，通过皮肤镜手动测量每位受试者的头皮头发密度。对数据进行比较以评估疗效。
我们的干预后头发密度增加了19.17%（治疗前为172.46±59.04根/平方厘米，6个月后为205.53±68.20根/平方厘米），短期副作用极小。III型头顶是反应最差的类型，且未观察到阳性反应与患者年龄或AGA病程之间存在相关性。
对男性AGA患者注射富血小板血浆对头发密度有积极影响。
