Wu Qian, Ying Jun, Xue Chenglan, Lv Qiang, Song Feng, Wang Jun, Song Xingbo, Chen Jie
Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.
Department of Clinical Laboratory, Santai People's Hospital, Santai 621100, Sichuan, China.
Leg Med (Tokyo). 2020 May 5;45:101714. doi: 10.1016/j.legalmed.2020.101714.
This study reported the forensic parameters of the 29 Y-STR loci of 242 unrelated Qiang males in Beichuan Qiang Autonomous County. Qiang population is a minority with small size populations and has never been reported. The overall haplotype diversity of Qiang population was measured to be 0.9992 while a discrimination capacity was 0.9215. According to the haplotypic analysis of the 29 Y-STR loci, 223 different haplotypes were obtained, of which 207 (92.83%) were unique. A total of 242 different alleles were checked at all loci, the corresponding allele frequencies ranged from 0.0041 to 0.7603. In addition, pairwise genetic distances, multidimensional scaling plots and neighbor-joining dendrogram were performed to analyze interpopulation differentiation between Qiang population and 16 other ethnic groups. These data can fill the gap in the Y-STR Haplotype Reference Database of the Qiang population and may be of reference value for forensic and population genetic analysis.
本研究报道了北川羌族自治县242名无关羌族男性29个Y-STR基因座的法医学参数。羌族是一个人口规模较小的少数民族，此前从未有过相关报道。测得羌族群体的单倍型多样性为0.9992，鉴别能力为0.9215。根据对29个Y-STR基因座的单倍型分析，共获得223种不同单倍型，其中207种（92.83%）为独有单倍型。所有基因座共检测到242个不同等位基因，相应的等位基因频率范围为0.0041至0.7603。此外，还进行了成对遗传距离、多维标度图和邻接法树状图分析，以研究羌族群体与其他16个民族之间的群体间差异。这些数据可填补羌族群体Y-STR单倍型参考数据库的空白，可能为法医学和群体遗传学分析提供参考价值。
