Castrup W, Wannenmacher M, Niedorf H R
Strahlentherapie. 1977 Apr;153(4):241-4.
Histological preparations from 22 irradiated patients with gigantofollicular lymphoblastoma Brill-Symmers have been reviewed and graded in accordance with the Kiel classification 1974. Corresponding to this, 19 patients had centroblastic-centrocytic lymphoma and three a centroblastic sarcoma. In the three sub-groups of centroblastic-centrocylic lymphomas, no essential differences were found in stages I-III with respect to anamnesis or clinical findings before the onset of treatment, or to the previous course of the disease. Centroblastic sarcoma, ranging among the lymphomas with a high degree of malignancy, has manifested unfavorable progressive courses in all patients.
对22例接受过放疗的巨滤泡性淋巴母细胞瘤（Brill-Symmers型）患者的组织学标本进行了回顾，并根据1974年的基尔分类法进行了分级。相应地，19例患者患有中心母细胞-中心细胞淋巴瘤，3例患有中心母细胞肉瘤。在中心母细胞-中心细胞淋巴瘤的三个亚组中，在治疗开始前的病史、临床表现或疾病既往病程方面，I-III期未发现本质差异。中心母细胞肉瘤属于高度恶性的淋巴瘤，所有患者均表现出不良的进展过程。
