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原发性骨淋巴瘤:儿童跟骨间变性大细胞淋巴瘤1例罕见病例

Primary Bone Lymphoma: A Rare Case of Anaplastic Large Cell Lymphoma in Calcaneus in a Child.

作者信息

Barik Sitanshu, Goyal Nikhil, Paul Souvik, Singh Vivek, Arora Shobha

机构信息

Department of Orthopedics, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.

出版信息

J Orthop Case Rep. 2019;9(4):14-18. doi: 10.13107/jocr.2019.v09.i04.1458.

Abstract

INTRODUCTION

Primary bone lymphomas are rare, and primary anaplastic large cell lymphomas (ALCLs) of bone in a child are even rarer. A case of primary ALCL of calcaneus in a 7-year-old child is presented.

CASE REPORT

Child aged 7 years presented with fungating swelling over his right heel which was associated with fever. The diagnosis was established by immunohistochemistry (CD30, ALK) of the biopsied specimen. Treatment was done by chemotherapy and subsequent radiotherapy. At 12-month follow-up, the child was ambulant with complete resolution of the swelling.

CONCLUSION

Masses arising from the foot and ankle can be a diagnostic challenge, and both infection and neoplasm should be considered in its differentials.

摘要

引言

原发性骨淋巴瘤较为罕见,儿童原发性骨间变性大细胞淋巴瘤(ALCL)则更为罕见。本文报告一例7岁儿童跟骨原发性ALCL病例。

病例报告

一名7岁儿童,右足跟出现溃疡性肿胀并伴有发热。通过对活检标本进行免疫组织化学检查(CD30、ALK)确诊。采用化疗及后续放疗进行治疗。随访12个月时,患儿可行走,肿胀完全消退。

结论

足踝部肿物的诊断具有挑战性,鉴别诊断时应考虑感染和肿瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/084a/7210905/500796b741ea/JOCR-9-14-g001.jpg

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