以广泛骨受累为表现的ALK阳性间变性大细胞淋巴瘤
ALK Positive Anaplastic Large Cell Lymphoma Presenting as Extensive Bone Involvement.
作者信息
Gajendra Smeeta, Sachdev Ritesh, Lipi Lipika, Goel Shalini, Misra Ruchira
机构信息
Attending Consultant, Department of Pathology and Laboratory Medicine, Medanta-The Medicity , Sector -38, Gurgaon, Haryana, India .
Senior Consultant, Department of Pathology and Laboratory Medicine, Medanta-The Medicity , Sector -38, Gurgaon, Haryana, India .
出版信息
J Clin Diagn Res. 2015 Jan;9(1):XD04-XD05. doi: 10.7860/JCDR/2015/11180.5437. Epub 2015 Jan 1.
Abstract
Anaplastic lymphoma kinase (ALK) positive Anaplastic large cell lymphoma (ALCL) represents approximately 2% of all Non-Hodgkin's lymphomas that commonly involves nodal as well as a wide variety of extra nodal sites, as skin, soft tissue, bones and lungs, although primary or secondary involvement of bone is rare. Herein, we report a case of 14-year-old female child presented as extensive bony involvement with a clinical diagnosis of bone tumour/ small round cell tumour, which was proved to be ALK positive ALCL on histopathological examination.
摘要
间变性淋巴瘤激酶（ALK）阳性间变性大细胞淋巴瘤（ALCL）约占所有非霍奇金淋巴瘤的2%，通常累及淋巴结以及多种结外部位，如皮肤、软组织、骨骼和肺部，尽管骨骼的原发性或继发性受累很少见。在此，我们报告一例14岁女童，以广泛的骨受累表现，临床诊断为骨肿瘤/小圆细胞肿瘤，经组织病理学检查证实为ALK阳性ALCL。
相似文献
1
ALK Positive Anaplastic Large Cell Lymphoma Presenting as Extensive Bone Involvement.以广泛骨受累为表现的ALK阳性间变性大细胞淋巴瘤
J Clin Diagn Res. 2015 Jan;9(1):XD04-XD05. doi: 10.7860/JCDR/2015/11180.5437. Epub 2015 Jan 1.
2
Primary bone anaplastic lymphoma kinase positive anaplastic large-cell lymphoma: A case report and review of the literature.原发性骨间变性淋巴瘤激酶阳性间变性大细胞淋巴瘤：1例病例报告并文献复习
World J Clin Cases. 2021 May 16;9(14):3403-3410. doi: 10.12998/wjcc.v9.i14.3403.
3
Anaplastic Lymphoma Kinase- and CD30-Positive Anaplastic Large-Cell Lymphoma of the External Auditory Canal.外耳道间变性淋巴瘤激酶和CD30阳性间变性大细胞淋巴瘤
Diagnostics (Basel). 2021 Jul 6;11(7):1220. doi: 10.3390/diagnostics11071220.
4
ALK-positive anaplastic large cell lymphoma with soft tissue involvement in a young woman.一名年轻女性患伴有软组织受累的ALK阳性间变性大细胞淋巴瘤。
Onco Targets Ther. 2016 Jul 1;9:3993-6. doi: 10.2147/OTT.S109746. eCollection 2016.
5
MUC1 (EMA) is preferentially expressed by ALK positive anaplastic large cell lymphoma, in the normally glycosylated or only partly hypoglycosylated form.MUC1（上皮膜抗原）在ALK阳性间变性大细胞淋巴瘤中优先以正常糖基化或仅部分低聚糖基化的形式表达。
J Clin Pathol. 2001 Dec;54(12):933-9. doi: 10.1136/jcp.54.12.933.
6
Anaplastic large cell lymphoma: an unusual presentation in a 7-year-old girl.间变性大细胞淋巴瘤：一名7岁女孩的不寻常表现。
Pediatr Dermatol. 2012 Jul-Aug;29(4):498-503. doi: 10.1111/j.1525-1470.2011.01465.x. Epub 2011 Oct 4.
7
A 15-Year-Old Boy with Primary Maxillary Bone Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma Relapsed with Rib Metastasis after Spontaneous Remission of a Maxillary Bone Lesion: A Case Report and Literature Review.一名15岁男孩，原发性上颌骨间变性淋巴瘤激酶阳性间变性大细胞淋巴瘤，上颌骨病变自发缓解后出现肋骨转移复发：病例报告及文献复习
Case Rep Oncol. 2023 May 12;16(1):308-314. doi: 10.1159/000530459. eCollection 2023 Jan-Dec.
8
Pathobiology of NPM-ALK and variant fusion genes in anaplastic large cell lymphoma and other lymphomas.间变性大细胞淋巴瘤及其他淋巴瘤中NPM-ALK和变异融合基因的病理生物学
Leukemia. 2000 Sep;14(9):1533-59. doi: 10.1038/sj.leu.2401878.
9
Differential expression of thymus and activation regulated chemokine and its receptor CCR4 in nodal and cutaneous anaplastic large-cell lymphomas and Hodgkin's disease.胸腺与激活调节趋化因子及其受体CCR4在淋巴结和皮肤间变性大细胞淋巴瘤及霍奇金病中的差异表达
Mod Pathol. 2002 Aug;15(8):838-44. doi: 10.1097/01.MP.0000021006.53593.B0.
10
Anaplastic large cell lymphoma of the palate: A case report.腭部间变大细胞淋巴瘤：一例报告。
J Stomatol Oral Maxillofac Surg. 2019 Apr;120(2):172-175. doi: 10.1016/j.jormas.2018.09.003. Epub 2018 Oct 3.
引用本文的文献
1
Systemic ALK-positive anaplastic large cell lymphoma involving implant site: a fortuitous association.累及植入部位的系统性ALK阳性间变性大细胞淋巴瘤：一种偶然关联。
Autops Case Rep. 2021 Aug 20;11:e2021296. doi: 10.4322/acr.2021.296. eCollection 2021.
2
Primary Bone Lymphoma: A Rare Case of Anaplastic Large Cell Lymphoma in Calcaneus in a Child.原发性骨淋巴瘤：儿童跟骨间变性大细胞淋巴瘤1例罕见病例
J Orthop Case Rep. 2019;9(4):14-18. doi: 10.13107/jocr.2019.v09.i04.1458.
3
A case of Primary Bone Anaplastic Large Cell Lymphoma.原发性骨间变性大细胞淋巴瘤1例。
Am J Case Rep. 2016 Oct 12;17:734-738. doi: 10.12659/ajcr.898743.
本文引用的文献
1
Anaplastic lymphoma kinase-positive anaplastic large cell lymphoma: current and future perspectives in adult and paediatric disease.间变性淋巴瘤激酶阳性间变性大细胞淋巴瘤：成人和儿童疾病的现状与未来展望
Eur J Haematol. 2014 Dec;93(6):455-68. doi: 10.1111/ejh.12360. Epub 2014 May 21.
2
Primary bone lymphoma: report of a case with multifocal skeletal involvement.原发性骨淋巴瘤：一例多灶性骨骼受累病例报告。
Biomed Imaging Interv J. 2007 Oct;3(4):e52. doi: 10.2349/biij.3.4.e52. Epub 2007 Oct 1.
3
Gene-expression profiling of systemic anaplastic large-cell lymphoma reveals differences based on ALK status and two distinct morphologic ALK+ subtypes.系统性间变性大细胞淋巴瘤的基因表达谱分析揭示了基于ALK状态和两种不同形态学ALK阳性亚型的差异。
Blood. 2007 Mar 1;109(5):2156-64. doi: 10.1182/blood-2006-06-028969. Epub 2006 Oct 31.
4
Anaplastic large-cell lymphoma, T-/null-cell type.间变性大细胞淋巴瘤，T/无细胞型。
Oncologist. 2006 Jul-Aug;11(7):831-40. doi: 10.1634/theoncologist.11-7-831.
5
Classification of cytotoxic T-cell and natural killer cell lymphomas.细胞毒性T细胞淋巴瘤和自然杀伤细胞淋巴瘤的分类。
Semin Hematol. 2003 Jul;40(3):175-84. doi: 10.1016/s0037-1963(03)00132-x.
6
Anaplastic large cell lymphomas presented as bone lesions: a clinicopathologic study of six cases and review of the literature.间变性大细胞淋巴瘤表现为骨病变：6例临床病理研究及文献复习
Mod Pathol. 2000 Oct;13(10):1143-9. doi: 10.1038/modpathol.3880211.
7
Childhood non-Hodgkin lymphomas in the United Kingdom: findings from the UK Children's Cancer Study Group.英国儿童非霍奇金淋巴瘤：英国儿童癌症研究小组的研究结果
J Clin Pathol. 1997 Feb;50(2):128-34. doi: 10.1136/jcp.50.2.128.
Zotero 插件