Gajendra Smeeta, Sachdev Ritesh, Lipi Lipika, Goel Shalini, Misra Ruchira
Attending Consultant, Department of Pathology and Laboratory Medicine, Medanta-The Medicity , Sector -38, Gurgaon, Haryana, India .
Senior Consultant, Department of Pathology and Laboratory Medicine, Medanta-The Medicity , Sector -38, Gurgaon, Haryana, India .
J Clin Diagn Res. 2015 Jan;9(1):XD04-XD05. doi: 10.7860/JCDR/2015/11180.5437. Epub 2015 Jan 1.
Anaplastic lymphoma kinase (ALK) positive Anaplastic large cell lymphoma (ALCL) represents approximately 2% of all Non-Hodgkin's lymphomas that commonly involves nodal as well as a wide variety of extra nodal sites, as skin, soft tissue, bones and lungs, although primary or secondary involvement of bone is rare. Herein, we report a case of 14-year-old female child presented as extensive bony involvement with a clinical diagnosis of bone tumour/ small round cell tumour, which was proved to be ALK positive ALCL on histopathological examination.
间变性淋巴瘤激酶（ALK）阳性间变性大细胞淋巴瘤（ALCL）约占所有非霍奇金淋巴瘤的2%，通常累及淋巴结以及多种结外部位，如皮肤、软组织、骨骼和肺部，尽管骨骼的原发性或继发性受累很少见。在此，我们报告一例14岁女童，以广泛的骨受累表现，临床诊断为骨肿瘤/小圆细胞肿瘤，经组织病理学检查证实为ALK阳性ALCL。
