无法挽救的肢体：两例骨肉瘤纤维母细胞变体病例报告
The Limb beyond Salvage: A Case Report on Two Cases of Fibroblastic Variants of Osteosarcoma.
作者信息
Edmund Der Muonir, Buunaaim A D B, Mikdad R, Tolgou Y
机构信息
Department of Pathology, School of Medicine and Health Science of the University for Development Studies and the Tamale Teaching Hospital, Ghana, West Africa.
Department of Surgery, School of Medicine and Health Science of the University for Development Studies and the Tamale Teaching Hospital, Ghana, West Africa.
出版信息
J Orthop Case Rep. 2019;9(4):96-100. doi: 10.13107/jocr.2019.v09.i04.1498.
INTRODUCTION
Management outcome of osteosarcoma as a primary bone malignancy is challenged in Ghana by many factors. We presented two male patients; aged 18 and 14 years, respectively, who were referred to the Tamale Teaching Hospital with advanced right knee tumors. Both patients had above knee amputation as part of treatment. The tumors were confirmed histologically as fibroblastic variants of osteosarcoma. The patients died within the immediate post-operative period without the initiation of the appropriate chemotherapy.
CONCLUSION
Unacceptable delay diagnosis and management of cancers worsened survival of patients. Education of patients, health workers and others along the patient management chain on the need early reporting and accurate diagnosis and management are recommended.
引言
在加纳，骨肉瘤作为一种原发性骨恶性肿瘤，其治疗结果受到多种因素的挑战。我们介绍了两名男性患者，分别为18岁和14岁，他们因右膝部晚期肿瘤被转诊至塔马利教学医院。两名患者均接受了膝上截肢作为治疗的一部分。肿瘤经组织学确诊为骨肉瘤的纤维母细胞变体。患者在术后即刻死亡，未开始适当的化疗。
结论
癌症诊断和治疗的不可接受的延迟使患者的生存率恶化。建议对患者、卫生工作者以及患者管理链上的其他人员进行教育，使其了解早期报告、准确诊断和管理的必要性。
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