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脊柱手术后失明:文献综述及 1 例病例讨论。

Amaurosis after spine surgery: survey of the literature and discussion of one case.

机构信息

Department of Neurosurgery, University Hospital Basel, Basel, Switzerland.

出版信息

Eur Spine J. 2011 Feb;20(2):171-6. doi: 10.1007/s00586-010-1557-9. Epub 2010 Sep 1.

Abstract

Postoperative vision loss (POVL) associated with spine surgery is a well known, albeit very rare complication. POVL incidence after spinal surgery ranges from 0.028 to 0.2%; however, due to the increase in number and duration of annual complex spinal operations, the incidence may increase. Origin and pathogenesis of POVL remain frequently unknown. A 73-year-old patient presented with lumbar disc herniation with associated neurological deficits after conservative pre-treatment at a peripheral hospital. Known comorbidities included arterial hypertension, moderate arterial sclerosis, diabetes mellitus type 2, mildly elevated blood lipids and treated prostate gland cancer. During lumbar spine surgery in modified prone position the patient presented with an acute episode of severe hypotension, which required treatment with catecholamines and Trendelenburg positioning. Three hours postoperatively, a visual loss in the right eye occurred, resulting in a complete amaurosis. Antihypertensive medication, arteriosclerosis and intraoperative hypotension are possible causes for the POVL. Intraoperative administration of catecholamines and Trendelenburg positioning for treatment of systemic hypotension might further compromise ocular perfusion. In patients with comorbidities compromising arterial blood pressure, blood circulation and microcirculation, POVL must be considered as a severe postoperative complication. It is recommended to inform patients about such complications and obtain preoperative informed consent regarding POVL. Any recent modification of antihypertensive medication must be reported and analysed for potential intraoperative hemodynamic consequences, prior to spine surgery in prone position.

摘要

与脊柱手术相关的术后视力丧失(POVL)是一种众所周知的罕见并发症。脊柱手术后 POVL 的发生率为 0.028 至 0.2%;然而,由于每年复杂脊柱手术的数量和持续时间增加,发生率可能会上升。POVL 的起源和发病机制仍常常未知。一名 73 岁的患者在一家外围医院进行保守治疗后出现腰椎间盘突出症并伴有神经功能缺损。已知的合并症包括动脉高血压、中度动脉粥样硬化、2 型糖尿病、血脂轻度升高和前列腺癌已治疗。在改良俯卧位进行腰椎手术时,患者出现严重低血压急性发作,需要使用儿茶酚胺和特伦德伦堡体位治疗。术后 3 小时,右眼出现视力丧失,导致完全失明。降压药物、动脉硬化和术中低血压可能是 POVL 的原因。为治疗全身低血压而术中给予儿茶酚胺和特伦德伦堡体位可能会进一步损害眼灌注。在合并症影响动脉血压、血液循环和微循环的患者中,必须将 POVL 视为严重的术后并发症。建议告知患者此类并发症,并在接受俯卧位脊柱手术前获得关于 POVL 的术前知情同意。任何最近对降压药物的修改都必须报告并分析其潜在的术中血流动力学后果。

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