对使用不同表面处理方法插入椎骨的钛螺钉的骨传导性进行比较。

A comparison of bone conductivity on titanium screws inserted into the vertebra using different surface processing.

作者信息

Ota Takashi, Demura Satoru, Kato Satoshi, Yoshioka Katsuhito, Hayashi Hiroyuki, Inoue Kei, Shinmura Kazuya, Yokogawa Noriaki, Shirai Toshiharu, Murakami Hideki, Tsuchiya Hiroyuki

机构信息

Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, 13-1, Takara-machi, Kanazawa, 920-8641, Japan.

Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan.

出版信息

J Exp Orthop. 2020 May 13;7(1):29. doi: 10.1186/s40634-020-00250-w.

DOI:10.1186/s40634-020-00250-w

PMID:32405666

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7221053/

Abstract

PURPOSE

Antibacterial iodine-supported titanium has an anodized oxide layer; thus, it can be expected to have a higher osteoconductivity than untreated titanium. This study aimed to compare the osteoconductivity between untreated titanium (Ti), anodically oxidized titanium (AO-Ti), and iodine-supported titanium (I-Ti) screws.

METHODS

The screws were inserted into the vertebral bodies of 30 dogs (12 for the biomechanical, and 18 for the histological examination). The vertebral bodies were analyzed at 4 or 8 weeks after screw insertion. Biomechanically, rotational torque of the screw was measured. Histologically, bone formation index (ratio of the length of the part where the bone directly contacts with the length of the screw) and bone volume density (ratio of the area of the bone tissue to the area between the threads of the screw) were measured.

RESULT

At 4 weeks, the torque value was significantly higher in the AO-Ti (0.59 ± 0.16 Nm) and I-Ti (0.72 ± 0.14 Nm) groups than in the Ti group (0.39 ± 0.12 Nm), with the AO-Ti and I-Ti groups showing no significant difference. Bone formation index was significantly higher in the AO-Ti (72.5% ± 0.8%) and I-Ti (73.4% ± 1.5%) groups than in the Ti group (64.6% ±1.7%), with the AO-Ti and I-Ti groups showing no significant difference. Bone volume density did not show a significant difference. At 8 weeks, the results were similar to those at 4 weeks.

CONCLUSIONS

I-Ti had a higher osteoconductivity than Ti, indicating that iodine coating did not adversely affect osteoconductivity.

摘要

目的

载碘钛具有阳极氧化氧化层；因此，可以预期其具有比未处理钛更高的骨传导性。本研究旨在比较未处理钛（Ti）、阳极氧化钛（AO-Ti）和载碘钛（I-Ti）螺钉之间的骨传导性。

方法

将螺钉植入30只犬的椎体（12只用于生物力学研究，18只用于组织学检查）。在螺钉植入后4周或8周对椎体进行分析。生物力学方面，测量螺钉的旋转扭矩。组织学方面，测量骨形成指数（骨直接接触部分的长度与螺钉长度的比值）和骨体积密度（骨组织面积与螺钉螺纹间面积的比值）。

结果

在4周时，AO-Ti组（0.59±0.16 Nm）和I-Ti组（0.72±0.14 Nm）的扭矩值显著高于Ti组（0.39±0.12 Nm），AO-Ti组和I-Ti组之间无显著差异。AO-Ti组（72.5%±0.8%）和I-Ti组（73.4%±1.5%）的骨形成指数显著高于Ti组（64.6%±1.7%），AO-Ti组和I-Ti组之间无显著差异。骨体积密度无显著差异。在8周时，结果与4周时相似。