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异常躯体体验问卷检测到的躯体异常在精神分裂症中比有精神病特征的双相情感障碍更频繁、更严重。

Abnormal bodily experiences detected by Abnormal Bodily Phenomena questionnaire are more frequent and severe in schizophrenia than in bipolar disorder with psychotic features.

机构信息

Department of Psychological, Humanistic and Territorial Sciences, G. D'Annunzio University, Chieti, Italy.

D. Portales University, Santiago, Chile.

出版信息

Eur Psychiatry. 2020 May 14;63(1):e49. doi: 10.1192/j.eurpsy.2020.49.

DOI:10.1192/j.eurpsy.2020.49
PMID:32406349
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7355172/
Abstract

BACKGROUND

Patients with schizophrenia display experiential anomalies in their feelings and cognitions arising in the domain of their lived body. These abnormal bodily phenomena (ABP) are not part of diagnostic criteria for schizophrenia. One of the reasons is the difficulty to assess specific ABP for schizophrenia spectrum disorders. The present study aimed to explore the presence in patients with schizophrenia of specific ABP.

METHODS

We used a semistructured interview-the Abnormal Bodily Phenomena questionnaire (ABPq), an instrument devised to detect and measure ABP specific to patients with schizophrenia. Fifty-one outpatients affected by schizophrenia and 28 euthymic outpatients affected by bipolar disorder type I with psychotic features (BD-pf-e) were recruited. Before assessing the specificity for schizophrenia of the observed ABP, we tested the internal consistency and the convergent validity of the ABPq in patients with schizophrenia. Specificity was assessed by examining potential differences in ABPq among the patients with schizophrenia in remission (SCZ-r) and BD-pf-e.

RESULTS

The ABPq shows strong internal consistency and convergent validity. As to the specificity, ABP measured by ABPq were more frequent and severe in SCZ-r than in BD-pf-e. In particular, all ABPq dimensions, except "Coherence," had at least mild severity in over 50% of SCZ-r, while dimensions with at least mild severity were observed in 5-10% of the BD-pf-e.

CONCLUSIONS

These findings can contribute to establish more precise phenomenal boundaries between schizophrenia and bipolar disorder, to explore the borders between nonpsychotic and psychotic forms of ABP, between ABP and negative and disorganized symptoms, and to enlighten core aspects of schizophrenia.

摘要

背景

精神分裂症患者在其生活体验中表现出感觉和认知的异常,这些异常的身体现象(ABP)不属于精神分裂症的诊断标准。原因之一是难以评估精神分裂症谱系障碍的特定 ABP。本研究旨在探讨精神分裂症患者是否存在特定的 ABP。

方法

我们使用半结构化访谈——异常身体现象问卷(ABPq),这是一种用于检测和测量精神分裂症患者特定 ABP 的工具。共招募了 51 名精神分裂症门诊患者和 28 名有精神病特征的双相情感障碍 I 型缓解期患者(BD-pf-e)。在评估观察到的 ABP 对精神分裂症的特异性之前,我们测试了精神分裂症患者 ABPq 的内部一致性和收敛效度。通过检查缓解期精神分裂症患者(SCZ-r)和 BD-pf-e 之间 ABPq 的潜在差异来评估特异性。

结果

ABPq 具有很强的内部一致性和收敛效度。就特异性而言,SCZ-r 患者的 ABPq 测量的 ABP 比 BD-pf-e 更频繁和严重。特别是,除了“一致性”之外,ABPq 的所有维度在超过 50%的 SCZ-r 中至少有轻度严重程度,而在 5-10%的 BD-pf-e 中观察到至少有轻度严重程度的维度。

结论

这些发现有助于在精神分裂症和双相情感障碍之间建立更精确的现象边界,探索非精神病和精神病形式的 ABP 之间的边界,以及 ABP 与阴性和紊乱症状之间的边界,并阐明精神分裂症的核心方面。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9737/7355172/21f431feab2d/S0924933820000498_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9737/7355172/21f431feab2d/S0924933820000498_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9737/7355172/21f431feab2d/S0924933820000498_fig1.jpg

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