N1-葡萄糖苷作为磺胺嘧啶、磺胺甲嘧啶和磺胺甲恶唑的尿液代谢产物。
N1-glucosides as urinary metabolites of sulphadimidine, sulphamerazine and sulphamethoxazole.
作者信息
Ahmad B, Powell J W
机构信息
Department of Pharmaceutical Chemistry, School of Pharmacy, London, U.K.
出版信息
Eur J Drug Metab Pharmacokinet. 1988 Jul-Sep;13(3):177-83. doi: 10.1007/BF03189937.
PMID:3240763
Abstract
The synthesis and characterisation of the N1-beta-D-glucosides of the three title sulphonamides are described, and these conjugates are shown, by means of HPLC and MS, to be minor urinary metabolites of these drugs.
摘要
描述了三种标题磺酰胺的N1-β-D-葡糖苷的合成与表征，并且通过高效液相色谱法和质谱法表明这些缀合物是这些药物的次要尿液代谢物。
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