Departamento de Química, Facultad de Ciencias, Universidad Nacional de Colombia-sede Bogotá, Carrera 30 # 45-03, Bogotá 111321, Colombia.
Molecules. 2020 May 12;25(10):2275. doi: 10.3390/molecules25102275.
The synthesis of phenyl-resorcinarenes and pyrogallolarenes is known to produce a conformational mixture of cone and chair isomers. Depending on the synthesis conditions the composition of the conformational mixture is variable; however, the cone conformer is the greatest proportion of phenyl-resorcin[4]arenes and chair conformer of pyrogallol[4]arenes. The experimental evidence suggests that phenyl-substituted resorcinarene and pyrogallolarene exist as a dynamic boat in solution.
苯并[4,5]间苯二酚并[4,5]菲咯啉和苯并[4,5]间苯二酚并[4,5]萘咯啉的合成已知会产生锥形和椅型异构体的构象混合物。根据合成条件的不同，构象混合物的组成是可变的；然而，苯并[4,5]间苯二酚并[4,5]菲咯啉的锥形构象是最大的比例，而苯并[4,5]间苯二酚并[4,5]萘咯啉的椅型构象是最大的比例。实验证据表明，取代的苯并[4,5]间苯二酚并[4,5]菲咯啉和苯并[4,5]间苯二酚并[4,5]萘咯啉在溶液中以动态船型存在。
