Robin M, Liang H, Baudouin C, Labbé A
Service d'ophtalmologie 3, centre hospitalier national d'ophtalmologie des Quinze-Vingts, 28, rue de Charenton, 75012 Paris, France; CHNO des Quinze-Vingts, IHU FOReSIGHT, Inserm-DGOS CIC 1423, 17, rue Moreau, 75012 Paris, France.
Service d'ophtalmologie 3, centre hospitalier national d'ophtalmologie des Quinze-Vingts, 28, rue de Charenton, 75012 Paris, France; CHNO des Quinze-Vingts, IHU FOReSIGHT, Inserm-DGOS CIC 1423, 17, rue Moreau, 75012 Paris, France; Inserm, CNRS, institut de la vision, Sorbonne universités, 17, rue Moreau, 75012 Paris, France.
J Fr Ophtalmol. 2020 Jun;43(6):484-493. doi: 10.1016/j.jfo.2019.10.009. Epub 2020 May 11.
Meibomian gland dysfunction (MGD) encompasses a group of complex pathologies of the ocular surface. They represent one of the main etiologies of dry eye but also one of the leading causes of consultation in ophthalmology. Conventional clinical tests (dry eye symptoms, tear film rupture time, glandular expressiveness assessment, or Schirmer's test) allow only an indirect assessment of Meibomian gland function and physiology. Various in vivo investigation methods have therefore been developed to image the meibomian glands such as meibography, optical coherence tomography, ultrasound or in vivo confocal microscopy. Some are accessible in clinical practice, while others remain in the field of clinical research. All these techniques aim to develop a direct structural analysis of the Meibomian glands to help in the diagnosis of DGM but also to better understand the pathophysiology of Meibomian glands. This review of the literature aims to provide an overview of existing imaging modalities and their interest in the evaluation of Meibomian glands and MGD.
睑板腺功能障碍(MGD)包括一组眼表的复杂病变。它们是干眼的主要病因之一,也是眼科门诊的主要就诊原因之一。传统的临床检查(干眼症状、泪膜破裂时间、睑板腺分泌能力评估或泪液分泌试验)只能间接评估睑板腺的功能和生理状态。因此,已经开发了各种体内研究方法来对睑板腺进行成像,如睑板腺造影、光学相干断层扫描、超声或活体共聚焦显微镜检查。有些方法在临床实践中可以使用,而其他方法仍处于临床研究领域。所有这些技术旨在对睑板腺进行直接的结构分析,以帮助诊断睑板腺功能障碍,同时更好地理解睑板腺的病理生理学。这篇文献综述旨在概述现有的成像方式及其在评估睑板腺和睑板腺功能障碍方面的意义。