Centre for Health Policy Studies, School of Public Health, School of Medicine, Zhejiang University, 866 Yuhangtang Road, Hangzhou, 310058, Zhejiang, China.
Center for Health Policy and Management Studies, School of Government, Nanjing University, Nanjing, Jiangsu, China.
Qual Life Res. 2020 Oct;29(10):2695-2704. doi: 10.1007/s11136-020-02524-3. Epub 2020 May 14.
To estimate the health-related quality of life (HRQoL) of type 2 diabetes (T2DM) inpatients hospitalized for a complication in China and to explore the associated factors.
This was a cross-sectional study. T2DM inpatients (aged ≥ 18 years) hospitalized for a complication, including ischemic heart disease (IHD), acute myocardial infarction (AMI), congestive heart failure (CHF), stroke, impaired vision, end-stage renal disease (ESRD), ulcer, and amputation were recruited from a tertiary hospital in China from January to May 2017. The EuroQoL-5 dimensions were used to measure HRQoL. A one-way analysis of variance and a multivariate regression analysis were performed.
Eight hundred and two T2DM inpatients hospitalized for a complication were included. The mean age was 62.67 years, and 43% of the inpatients were female. The mean utility-based HRQoL was 0.562 (95% CI 0.548, 0.577). The utility varied significantly between the complications: IHD = 0.620 (95% CI 0.597, 0.642), AMI = 0.434 (95% CI 0.394, 0.473), CHF = 0.471 (95% CI 0.433, 0.510), stroke = 0.472 (95% CI 0.436, 0.508), impaired vision = 0.714 (95% CI 0.692, 0.737), ESRD = 0.693 (95% CI 0.670, 0.717), ulcer = 0.431 (95% CI 0.375, 0.487), and amputation = 0.395 (95% CI 0.341, 0.448). Inpatients with a complication, who were female, and who had no daily exercise had a lower HRQoL.
The HRQoL of T2DM inpatients with a complication was considerably impaired. Our estimates provide supplementary data for public health and cost-effectiveness modeling, and increase the breadth of knowledge of HRQoL in T2DM.
评估中国住院 2 型糖尿病(T2DM)并发症患者的健康相关生活质量(HRQoL),并探讨其相关因素。
这是一项横断面研究。2017 年 1 月至 5 月,从中国一家三级医院招募了因缺血性心脏病(IHD)、急性心肌梗死(AMI)、充血性心力衰竭(CHF)、中风、视力障碍、终末期肾病(ESRD)、溃疡和截肢等并发症住院的 T2DM 患者(年龄≥18 岁)。采用 EuroQoL-5 维度量表测量 HRQoL。采用单因素方差分析和多因素回归分析。
共纳入 802 例因并发症住院的 T2DM 患者,平均年龄为 62.67 岁,43%为女性。基于效用的平均 HRQoL 为 0.562(95%CI 0.548,0.577)。并发症之间的效用差异显著:IHD=0.620(95%CI 0.597,0.642),AMI=0.434(95%CI 0.394,0.473),CHF=0.471(95%CI 0.433,0.510),中风=0.472(95%CI 0.436,0.508),视力障碍=0.714(95%CI 0.692,0.737),ESRD=0.693(95%CI 0.670,0.717),溃疡=0.431(95%CI 0.375,0.487),截肢=0.395(95%CI 0.341,0.448)。患有并发症的女性和没有日常锻炼的患者 HRQoL 较低。
T2DM 并发症患者的 HRQoL 明显受损。我们的估计为公共卫生和成本效益建模提供了补充数据,并增加了 T2DM 患者 HRQoL 的知识广度。