Reynolds Ciara M E, McMahon Léan E, O'Malley Eimer G, O'Brien Oliver, Sheehan Sharon R, Turner Michael J
UCD Centre for Human Reproduction, Coombe Women and Infants University Hospital, Dublin, Ireland.
UCD Centre for Human Reproduction, Coombe Women and Infants University Hospital, Dublin, Ireland.
Eur J Obstet Gynecol Reprod Biol. 2020 Jul;250:86-92. doi: 10.1016/j.ejogrb.2020.04.005. Epub 2020 Apr 28.
Epidemiological studies have previously reported that maternal socioeconomic disadvantage is associated with adverse feto-maternal outcomes. However, little attention has been paid to the question of the woman's employment status. The aim of this observational study was to examine the relationship between maternal employment status at the first antenatal visit and pregnancy outcomes.
The study was confined to women with a singleton pregnancy who attended for maternity care between the years 2010 and 2017 and delivered a baby weighing ≥500 g. Self-reported sociodemographic and clinical details were recorded at the first antenatal visit by a trained midwife and updated before hospital discharge. The hospital is one of the largest in Europe and accepts women from all socioeconomic groups, including women in the public system and those with private health insurance, across the rural-urban spectrum.
Of the 62,395 women, the mean age was 31.5 years (SD 5.4), 39.3% were nulliparas and 70.7% were Irish born. Compared with the 45,028 (72.2%) women who reported as being in paid employment, the 4984 (8.0%) women who were unemployed had a higher rate of stillbirth (8/4984 vs. 27/45,028, p = 0.005) and homemakers had a higher incidence of neonatal death (31/12,383 vs. 73/45,028, p = 0.02). On multivariable analysis, women who were unemployed or homemakers had increased adjusted odds ratios for neonatal unit (NNU) admissions, preterm birth, low birth weight, and small-for-gestational-age. Compared to women in paid employment, women who were unemployed or homemakers were associated with younger age (<30 years) in pregnancy, multiparity, unplanned pregnancy, no or postconceptional only folic acid supplementation, anxiolytic/antidepressant use, as well as persistent smoking and illicit drug use during pregnancy.
In a high-income European country, women who reported as unemployed or homemakers were associated with higher rates of adverse pregnancy outcomes. Furthermore, these women were associated with suboptimal lifestyle behaviours such as smoking and illicit drug use in early pregnancy. This highlights the need for long term public policies on female unemployment and retaining women with children in employment.
流行病学研究此前报告称,母亲的社会经济劣势与不良的母婴结局相关。然而,女性的就业状况问题却很少受到关注。这项观察性研究的目的是探讨首次产前检查时母亲的就业状况与妊娠结局之间的关系。
该研究仅限于2010年至2017年间前来接受产科护理并分娩出体重≥500克婴儿的单胎妊娠女性。由经过培训的助产士在首次产前检查时记录自我报告的社会人口统计学和临床详细信息,并在出院前更新。该医院是欧洲最大的医院之一,接收来自所有社会经济群体的女性,包括公共系统中的女性以及有私人医疗保险的女性,涵盖城乡范围。
在62395名女性中,平均年龄为31.5岁(标准差5.4),39.3%为初产妇,70.7%出生于爱尔兰。与报告有带薪工作的45028名(72.2%)女性相比,4984名(8.0%)失业女性的死产率更高(4984人中8例 vs. 45028人中27例,p = 0.005),家庭主妇的新生儿死亡率更高(12383人中31例 vs. 45028人中73例,p = 0.02)。多变量分析显示,失业或家庭主妇身份的女性入住新生儿重症监护病房(NNU)、早产、低出生体重和小于胎龄儿的校正比值比增加。与有带薪工作的女性相比,失业或家庭主妇身份的女性在孕期年龄较小(<30岁)、经产妇、意外怀孕、未补充或仅在受孕后补充叶酸、使用抗焦虑/抑郁药物,以及孕期持续吸烟和使用非法药物。
在一个高收入欧洲国家,报告为失业或家庭主妇的女性不良妊娠结局发生率较高。此外,这些女性与不良生活方式行为相关,如孕期早期吸烟和使用非法药物。这凸显了制定关于女性失业以及让有孩子的女性继续就业的长期公共政策的必要性。