腐生葡萄球菌及其他凝固酶阴性葡萄球菌的血细胞凝集作用

Hemagglutination by Staphylococcus saprophyticus and other coagulase-negative staphylococci.

作者信息

Beuth J, Ko H L, Schumacher-Perdreau F, Peters G, Heczko P, Pulverer G

机构信息

Institute of Hygiene, University of Cologne, FRG.

出版信息

Microb Pathog. 1988 May;4(5):379-83. doi: 10.1016/0882-4010(88)90065-4.

DOI:10.1016/0882-4010(88)90065-4

PMID:3241546

Abstract

Hemagglutination tests were performed to specify surface lectins (hemagglutinins) of four coagulase-negative staphylococcal species: S. saprophyticus (31 strains), S. epidermidis (5 strains), S. haemolyticus (3 strains), and S. warneri (3 strains). All strains of S. saprophyticus agglutinated sheep red blood cells (RBC) and the hemagglutination was inhibited by N-acetylglucosamine (GlcNAc) plus either N-acetylgalactosamine (GalNAc, 15 strains) or N-acetylneuraminic acid (NANA, 16 strains). Those strains showing inhibition by GalNAc also agglutinated horse RBC while those inhibited by NANA agglutinated rabbit RBC. The former type was more common among urinary tract isolates (10/15) and the second one among respiratory isolates (9/14). The eleven strains of other staphylococci agglutinated rabbit (and not sheep or horse) RBC; this hemagglutination was never inhibited by GlcNAc but instead by NANA alone or together with another sugar (7 strains) or by other sugars (4 strains, 3 different patterns of inhibition).

摘要

进行血凝试验以确定四种凝固酶阴性葡萄球菌的表面凝集素（血凝素）：腐生葡萄球菌（31株）、表皮葡萄球菌（5株）、溶血葡萄球菌（3株）和沃氏葡萄球菌（3株）。所有腐生葡萄球菌菌株均能凝集绵羊红细胞（RBC），且N-乙酰葡糖胺（GlcNAc）加N-乙酰半乳糖胺（GalNAc，15株）或N-乙酰神经氨酸（NANA，16株）可抑制血凝。那些显示被GalNAc抑制的菌株也能凝集马红细胞，而那些被NANA抑制的菌株能凝集兔红细胞。前一种类型在泌尿道分离株中更为常见（10/15），后一种类型在呼吸道分离株中更为常见（9/14）。其他葡萄球菌的11株菌株能凝集兔（而非绵羊或马）红细胞；这种血凝从未被GlcNAc抑制，而是单独被NANA或与另一种糖一起（7株）或被其他糖（4株，3种不同的抑制模式）抑制。