Vasantham Vyshnavi, Yadav Shakti Kumar, Sarin Namrata, Singh Sompal, Pruthi Sonam Kumar
Department of Pathology, North Delhi Municipal Corporation Medical College and Hindu Rao Hospital, New Delhi, India.
Department of Pathology, North Delhi Municipal Corporation Medical College and Hindu Rao Hospital, New Delhi, India.
Int J Surg Case Rep. 2020;70:56-59. doi: 10.1016/j.ijscr.2020.04.051. Epub 2020 May 11.
Filariasis is a major health problem in certain parts of India. Microfilaria detection on exfoliative and fluid cytology is extremely rare and it is even very rare to find microfilaria coexistent with neoplastic lesions.
A 45-year-old nulliparous female, who presented with complaints of lower abdominal swelling and pain. Initially, a clinical diagnosis of cystadenoma was made. Ascitic fluid cytology of the patient showed 3-dimensional clusters of cells along with an occasional microfilaria. On histopathology, a diagnosis of Mucinous cystadenocarcinoma of ovary was made.
Most common cause of lymphatic filariasis is W. bancrofti followed by Brugia species and it affects young adults. The adult form of the filaria lodge in lymph vessels, and due to lymphatic blockage in neoplasms they appear in tissue fluid or on surface material. It is the first case report of microfilaria being detected in ovarian cystic fluid cytology in a patient of Mucinous cystadenocarcinoma of ovary.
Filaria is an incidental finding in most of the cases, hence, cytopathologist should be vigilant and careful screening of all the slides should be done, especially in a country like India, where it is highly endemic.
丝虫病是印度某些地区的一个主要健康问题。在脱落细胞学和体液细胞学中检测到微丝蚴极为罕见，发现微丝蚴与肿瘤性病变共存的情况甚至更为罕见。
一名45岁未育女性，主诉下腹部肿胀和疼痛。最初临床诊断为囊腺瘤。患者的腹水细胞学检查显示有三维细胞团，偶见微丝蚴。组织病理学诊断为卵巢黏液性囊腺癌。
淋巴丝虫病最常见的病因是班氏吴策线虫，其次是布鲁氏菌属，它影响年轻人。丝虫的成虫寄生于淋巴管，由于肿瘤中的淋巴阻塞，它们出现在组织液或表面物质中。这是在一名卵巢黏液性囊腺癌患者的卵巢囊液细胞学中检测到微丝蚴的首例病例报告。
在大多数病例中，丝虫是一个偶然发现，因此，细胞病理学家应保持警惕，应对所有玻片进行仔细筛查，特别是在印度这样丝虫病高度流行的国家。
