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鳞状细胞癌植入游离皮瓣供区

Implantation of Squamous Cell Carcinoma in a Free Flap Donor Site.

作者信息

Pichardo Priscilla, Purdy Nicholas, Haugen Thorsen

机构信息

Department of Otolaryngology-Head & Neck Surgery, Geisinger Medical Center, Danville, PA, USA.

出版信息

Ann Otol Rhinol Laryngol. 2020 Sep;129(9):935-940. doi: 10.1177/0003489420917418. Epub 2020 May 17.

DOI:10.1177/0003489420917418
PMID:32419484
Abstract

INTRODUCTION

It is well known that malignant cells can be implanted at distant donor sites due to iatrogenic surgical contamination. Only a small number of reports, however, have been published describing this.

CASE PRESENTATION

We present a case of oral cavity Squamous Cell Carcinoma (SCC) reconstructed with a radial forearm free flap in which SCC developed in the subcutaneous tissues beneath the donor incision site 6 months after surgery.

MANAGEMENT

The implanted tumor was excised and the field was subsequently treated with radiation. The patient remains disease-free on follow-up.

DISCUSSION

We present the second report of tumor implanted in a free flap donor site. Additionally, we discuss the risks of tumor implantation, review the literature, and make recommendations to avoid this complication.

摘要

引言

众所周知,由于医源性手术污染,恶性细胞可植入远处供体部位。然而,仅有少数报告描述过这一情况。

病例介绍

我们报告一例口腔鳞状细胞癌(SCC)患者,该患者接受了桡侧前臂游离皮瓣重建术,术后6个月在供体切口部位下方的皮下组织中发生了SCC。

治疗

切除植入的肿瘤,随后对该区域进行放射治疗。患者在随访中无疾病复发。

讨论

我们报告了第二例肿瘤植入游离皮瓣供体部位的病例。此外,我们讨论了肿瘤植入的风险,回顾了相关文献,并提出了避免这一并发症的建议。

相似文献

1
Implantation of Squamous Cell Carcinoma in a Free Flap Donor Site.鳞状细胞癌植入游离皮瓣供区
Ann Otol Rhinol Laryngol. 2020 Sep;129(9):935-940. doi: 10.1177/0003489420917418. Epub 2020 May 17.
2
Novel technique for the direct closure of the radial forearm flap donor site defect with a local bilobed flap.应用局部双叶皮瓣直接闭合前臂皮瓣供区缺损的新方法。
Head Neck. 2019 Sep;41(9):3282-3289. doi: 10.1002/hed.25839. Epub 2019 Jun 11.
3
Squamous cell carcinoma arising on a forearm free flap 21 years after hemiglossectomy.半侧舌切除术后21年,在前臂游离皮瓣上发生的鳞状细胞癌。
Ann Ital Chir. 2016 Feb 4;87(ePub):S2239253X16024683.
4
Donor site morbidity and flap perfusion of subfascial and suprafascial radial forearm flaps: A randomized prospective clinical comparison trial.桡动脉前臂筋膜下和筋膜上组织瓣供区并发症及组织瓣灌注情况:一项随机前瞻性临床对比试验
J Craniomaxillofac Surg. 2016 Sep;44(9):1299-304. doi: 10.1016/j.jcms.2016.06.025. Epub 2016 Jul 2.
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One stage reconstruction of the floor of the mouth with a subcutaneous pedicled nasolabial flap.采用皮下蒂鼻唇沟皮瓣一期修复口底。
J Egypt Natl Canc Inst. 2012 Jun;24(2):71-6. doi: 10.1016/j.jnci.2012.02.002. Epub 2012 Apr 6.
6
The radial forearm free flap for head and neck reconstruction: a review.用于头颈部重建的桡侧前臂游离皮瓣:综述
Am J Surg. 1994 Nov;168(5):446-50. doi: 10.1016/s0002-9610(05)80096-0.
7
Mucosal prelamination of a radial forearm flap for intraoral reconstruction.用于口腔内重建的桡侧前臂皮瓣黏膜预层叠术。
J Reconstr Microsurg. 1997 Oct;13(7):507-13. doi: 10.1055/s-2007-1006432.
8
[The myofascial pectoralis major flap for tissue replacement in the oral cavity].[用于口腔组织替代的胸大肌肌筋膜瓣]
Laryngorhinootologie. 1994 Apr;73(4):193-7. doi: 10.1055/s-2007-997109.
9
Recurrence of cutaneous squamous cell carcinoma at remote limb donor site.肢体远位供皮区皮肤鳞状细胞癌复发。
J Plast Reconstr Aesthet Surg. 2012 Sep;65(9):1265-6. doi: 10.1016/j.bjps.2012.01.022. Epub 2012 Feb 21.
10
Free arterialised venous forearm flaps for intraoral reconstruction.用于口腔内重建的游离动脉化静脉前臂皮瓣
Br J Plast Surg. 1997 Apr;50(3):166-71. doi: 10.1016/s0007-1226(97)91364-3.

引用本文的文献

1
Oral Squamous Cell Carcinoma Metastasis to Anterolateral Thigh Flap Donor Site: A Case Report.口腔鳞状细胞癌转移至股前外侧皮瓣供区:一例报告
Plast Reconstr Surg Glob Open. 2023 Sep 19;11(9):e5278. doi: 10.1097/GOX.0000000000005278. eCollection 2023 Sep.
2
Left cheek sclerosing rhabdomyosarcoma and development of isolated free flap donor site metastasis.左侧颊部硬化性横纹肌肉瘤及孤立游离皮瓣供区转移。
BMJ Case Rep. 2022 Apr 7;15(4):e248390. doi: 10.1136/bcr-2021-248390.