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Neuroendocrine pancreatic tumor causing chronic diarrhea in young adult, a case report.神经内分泌胰腺肿瘤导致青年成人慢性腹泻:一例报告
AME Case Rep. 2020 Apr 30;4:13. doi: 10.21037/acr.2020.04.03. eCollection 2020.
2
Pancreatic Vasoactive Intestinal Peptide-Producing Tumor as a Rare Cause of Acute Diarrhea and Severe Hypokalemia.胰腺血管活性肠肽瘤作为急性腹泻和严重低钾血症的罕见病因
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Pancreatic VIPoma as a Differential Diagnosis in Chronic Pediatric Diarrhea: A Case Report and Review of the Literature.胰腺血管活性肠肽瘤作为小儿慢性腹泻的鉴别诊断:一例报告及文献复习
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Pancreatic VIPomas from China: Case reports and literature review.来自中国的胰腺血管活性肠肽瘤:病例报告和文献复习。
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A clinical analysis on functioning pancreatic neuroendocrine tumors (focusing on VIPomas): a single-center experience.功能性胰腺神经内分泌肿瘤(以 VIP 瘤为重点)的临床分析:单中心经验。
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Chronic Diarrhea Secondary to Newly Diagnosed VIPoma.新诊断的血管活性肠肽瘤继发慢性腹泻
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Intractable and dramatic diarrhea in liver transplantation recipient with vasoactive intestinal peptide-producing tumor after split liver transplantation: a case report.活体肝移植术后患有血管活性肠肽分泌肿瘤的肝移植受者出现难治性剧烈腹泻:一例报告
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Surgical resection of vasoactive intestinal peptideoma with hepatic metastasis aids symptom palliation: A case report.手术切除伴有肝转移的血管活性肠肽瘤有助于缓解症状:一例报告
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Dual Diagnostic Dilemma: Gitelman Syndrome and Incidental Neuroendocrine Tumor in a Young Adult With Refractory Hypokalemia.双重诊断困境:一名患有难治性低钾血症的年轻成年人的吉特曼综合征与偶发性神经内分泌肿瘤
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Pancreatic Vasoactive Intestinal Peptide-Producing Tumor as a Rare Cause of Acute Diarrhea and Severe Hypokalemia.胰腺血管活性肠肽瘤作为急性腹泻和严重低钾血症的罕见病因
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Treatment options of metastatic and nonmetastatic VIPoma: a review.转移性和非转移性 VIP 瘤的治疗选择:综述。
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本文引用的文献

1
Pancreatic neuroendocrine microadenomatosis presenting as a functional VIPoma.表现为功能性血管活性肠肽瘤的胰腺神经内分泌微腺瘤病
J Surg Case Rep. 2019 Jun 28;2019(6):rjz196. doi: 10.1093/jscr/rjz196. eCollection 2019 Jun.
2
Chronic Diarrhea Secondary to Newly Diagnosed VIPoma.新诊断的血管活性肠肽瘤继发慢性腹泻
Case Rep Gastroenterol. 2019 Apr 23;13(1):225-229. doi: 10.1159/000494554. eCollection 2019 Jan-Apr.
3
Percutaneous Irreversible Electroporation for Pancreatic VIPoma: A Case Report.经皮不可逆电穿孔治疗胰腺血管活性肠肽瘤:病例报告
Pancreas. 2017 Jan;46(1):135-137. doi: 10.1097/MPA.0000000000000698.

神经内分泌胰腺肿瘤导致青年成人慢性腹泻:一例报告

Neuroendocrine pancreatic tumor causing chronic diarrhea in young adult, a case report.

作者信息

Mendes Filho Otávio, Maués Carolina A D, De Macedo Frank P P C, Monteiro Saullo A C, Araújo Elaine F C, Rodriguez Juan E R, Cauduro Júlia F, Filó Maitê S, Bergamasco João J C, Silva Neto Rubem A, Silva Júnior Rubem A

机构信息

Digestive System Surgery Service at Getúlio Vargas Teaching Hospital (HUGV), Manaus, Amazonas, Brazil.

Medical School of Federal University of Amazonas (UFAM), Manaus, Amazonas, Brazil.

出版信息

AME Case Rep. 2020 Apr 30;4:13. doi: 10.21037/acr.2020.04.03. eCollection 2020.

DOI:10.21037/acr.2020.04.03
PMID:32420536
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7221343/
Abstract

Secretory tumors of vasoactive intestinal polypeptides (VIPomas) are rare neuroendocrine pancreatic neoplasms usually associated with secretory diarrhea. Most cases present themselves with diarrhea, weight loss, and hypokalemia. Although VIPoma patients share easily distinguishable symptoms, early diagnosis remains a challenge. Therefore, tumors are usually found in large proportions and with later staging. The presenting case portrays a unique situation where the tumor found was still in a small size, is worth reporting it to the current literature. The diagnosis was made through laboratory evaluation and imaging studies. The primary treatment consists of exeresis surgery, but cytoreductive surgery also can provide several benefits. This way is necessary to pay attention to diagnoses also in the ways of treatment.

摘要

血管活性肠肽分泌性肿瘤(VIPoma)是罕见的神经内分泌胰腺肿瘤,通常与分泌性腹泻有关。大多数病例表现为腹泻、体重减轻和低钾血症。尽管VIPoma患者有易于区分的症状,但早期诊断仍然是一项挑战。因此,肿瘤通常在较大比例的患者中被发现且分期较晚。本文呈现的病例描述了一种独特情况,即发现的肿瘤仍处于小尺寸状态,值得向当前文献报道。诊断通过实验室评估和影像学检查做出。主要治疗方法包括切除手术,但减瘤手术也可带来多种益处。在治疗过程中同样有必要关注诊断方法。