Mendes Filho Otávio, Maués Carolina A D, De Macedo Frank P P C, Monteiro Saullo A C, Araújo Elaine F C, Rodriguez Juan E R, Cauduro Júlia F, Filó Maitê S, Bergamasco João J C, Silva Neto Rubem A, Silva Júnior Rubem A
Digestive System Surgery Service at Getúlio Vargas Teaching Hospital (HUGV), Manaus, Amazonas, Brazil.
Medical School of Federal University of Amazonas (UFAM), Manaus, Amazonas, Brazil.
AME Case Rep. 2020 Apr 30;4:13. doi: 10.21037/acr.2020.04.03. eCollection 2020.
Secretory tumors of vasoactive intestinal polypeptides (VIPomas) are rare neuroendocrine pancreatic neoplasms usually associated with secretory diarrhea. Most cases present themselves with diarrhea, weight loss, and hypokalemia. Although VIPoma patients share easily distinguishable symptoms, early diagnosis remains a challenge. Therefore, tumors are usually found in large proportions and with later staging. The presenting case portrays a unique situation where the tumor found was still in a small size, is worth reporting it to the current literature. The diagnosis was made through laboratory evaluation and imaging studies. The primary treatment consists of exeresis surgery, but cytoreductive surgery also can provide several benefits. This way is necessary to pay attention to diagnoses also in the ways of treatment.
血管活性肠肽分泌性肿瘤(VIPoma)是罕见的神经内分泌胰腺肿瘤,通常与分泌性腹泻有关。大多数病例表现为腹泻、体重减轻和低钾血症。尽管VIPoma患者有易于区分的症状,但早期诊断仍然是一项挑战。因此,肿瘤通常在较大比例的患者中被发现且分期较晚。本文呈现的病例描述了一种独特情况,即发现的肿瘤仍处于小尺寸状态,值得向当前文献报道。诊断通过实验室评估和影像学检查做出。主要治疗方法包括切除手术,但减瘤手术也可带来多种益处。在治疗过程中同样有必要关注诊断方法。