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捷克共和国东波希米亚地区 2002-2017 年黑色素瘤的流行病学及年日照暴露的影响

Epidemiology of Melanoma in the Czech Republic in East Bohemia in the Period 2002-2017 and the Effect of the Annual Sunshine Exposure.

机构信息

Department of Dermatology and Venereology Faculty Hospital and Medical Faculty of Charles University, Hradec Králové, Czech Republic.

Department of Medical Biophysics, Medical Faculty of Charles University, Hradec Králové, Czech Republic.

出版信息

Acta Medica (Hradec Kralove). 2020;63(1):10-17. doi: 10.14712/18059694.2020.10.

Abstract

AIM

The evaluation of the trend in the occurrence of melanoma nodulare, melanoma superficiale, lentigo maligna and melanoma in situ in the period of 2002-2017 in East Bohemia region in the Czech Republic. We examine if the annual numbers of hours of sunshine could affect the number of patients with melanoma.

METHOD

In the peridod of 2002-2017, altogether 2230 patients with new diagnosis of melanoma were examined. We studied 1) If there is some trend in the occurrence of lentigo maligna and melanoma in situ, melanoma superficiale, and melanoma nodulare and if there is a difference in the age of patients with this diagnosis (adjusted calculation of specific kind of melanomas and adjusted calculation of age). 2) If the annual numbers of hours of sunshine affect the trend in the occurrence of melanoma and if the annual numbers of hours of sunshine affect the body site of melanoma.

RESULTS AND CONCLUSION

Our study confirmed that the number of patients with lentigo maligna and melanoma in situ had increased in East Bohemia region in the period of 2002-2017. The number of melanomas of nodular and superficial type does not increase. The total number of melanomas in this period does not increase either. No difference of the age of patients with melanoma nodulare, superficiale, lentigo maligna and melanoma in situ was confirmed. We confirmed no relation of the annual numbers of hours of sunshine to the number of melanoma and to the body site of melanoma.

摘要

目的

评估 2002-2017 年捷克共和国东波希米亚地区结节性黑素瘤、浅表性黑素瘤、恶性雀斑样痣和原位黑素瘤的发病趋势。我们研究了每年日照时数是否会影响黑素瘤患者的数量。

方法

在 2002-2017 年期间,共检查了 2230 例新诊断的黑素瘤患者。我们研究了 1)恶性雀斑样痣和原位黑素瘤、浅表性黑素瘤和结节性黑素瘤的发病是否存在某种趋势,以及该诊断患者的年龄是否存在差异(特定类型黑素瘤的调整计算和年龄的调整计算)。2)每年日照时数是否影响黑素瘤发病趋势,以及每年日照时数是否影响黑素瘤的发病部位。

结果与结论

研究证实,2002-2017 年东波希米亚地区恶性雀斑样痣和原位黑素瘤患者数量增加。结节型和浅表型黑素瘤的数量没有增加。在此期间,黑素瘤总数也没有增加。未证实结节性黑素瘤、浅表性黑素瘤、恶性雀斑样痣和原位黑素瘤患者的年龄存在差异。未证实每年日照时数与黑素瘤数量和黑素瘤发病部位之间存在关系。

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